Hematology

Question 1

What type of anemia that is characterized by the production of defective hemoglobin is known as

Answer 1

Sickle cell anemia

Question 2

Which one of the following does the coagulation cascade involve

Answer 2

prothrombin becomes thrombin

Question 3

Which one of the following factors does NOT affect the rate and degree of sickling in sickle cell anemia

Answer 3

an increase in blood pH

Question 4

Most immediate (type 1) allergic reactions are mediated by the production of

Answer 4

IgE antibodies

Question 5

A clinical syndrome in which a decreased number of circulating platelets (thrombocytopenia) manifests as a bleeding tendency is

Answer 5

Immune thrombocytopenia purpura

Question 6

The antibody that responds immediately increases during a hypersensitivity reaction is

Answer 6

IgE

Question 7

Which structure produces lymphocytes and guards the body against airborne and ingested pathogens

Answer 7

The tonsils

Question 8

An X-linked disorder caused by a deficiency in plasma clotting factors is

Answer 8

hemophilia

Question 9

Which of the following cells provide innate immunity, are the first line of defense against infection, and work to engulf and destroy invading organisms

Answer 9

macrophages

Question 10

Which cell releases histamine and cytokines when it degreanulates

Answer 10

mast cell

Question 11

Which of the following is the first immunoglobulin produced during an immune response

Answer 11

IgM

Question 12

Thrombocytopenia is characterized by

Answer 12

insufficient circulating platelets

Question 13

Which protein is an important mediator of the inflammatory response and serves as a messenger at the site of antigen (allergy) invasion

Answer 13

cytokines

Question 14

A condition in which clotting and hemorrhage occur at the same time within the vascular system is known as

Answer 14

Disseminated Intravascular Coagulation (DIC)

Question 15

The plasma protein that binds to and transports iron is known as

Answer 15

transferrin

Question 16

What is the average lifespan of a red cell

Answer 16

120 days

Question 17

Which of the following is NOT part of the immune system

Answer 17

the sinus tract

Question 18

What is the name of the protein that forms fibers that trap blood

Answer 18

fibrin

Question 19

A type of anemia caused by damage to stem cells in the bone marrow is known as

Answer 19

aplastic anemia

Question 20

The cells that are generated in the thymus and are instrumental in developing cellular immunity are

Answer 20

T cells

Question 21

Increased lead absorption is NOT present in

Answer 21

folic acid deficiency

Question 22

Which one of the following factors does NOT affect the rate and degree of sickling cell anemia

Answer 22

an increase in pH

Question 23

Which one of the following is a type of megaloblastic anemia

Answer 23

pernicious anemia

Question 24

The immunoglobulin (g) that functions as the major antibacterial and antiviral antibody is

Answer 24

IgG

Question 25

A heriditary type of hemolytic anemia that is caused impaired enzyme function is known as

Answer 25

Glucose-6 phosphate dehydrogenase

Question 26

Jaundice in a newborn is a medical emergency if it occurs within the first

Answer 26

24 hours

Question 27

Which one of the following blood lead levels in an adult would warrant intervention

Answer 27

20mcg/dl

Question 28

Which one of the following is the first immunoglobulin produced during an immune response

Answer 28

IgM

Question 29

Which hereditary disease leads to a hypercoagulable state

Answer 29

Factor 5 Leiden

Question 30

The immunoglobulin that plays a crucial role in the immune function of the mucous membrane is

Answer 30

IgA

Question 31

Which of the following is true about beta thalassemia

Answer 31

beta thalassemia may cause bone deformities of the face and skull

Question 32

A vital function of platelets is to

Answer 32

form hemostatic plugs in injured blood vessels

Question 33

Which of the following is NOT involved in hemostasis

Answer 33

destruction of collagen fibers

Question 34

What is the term for a genetic disorder passed from one parent to offspring and carried with an X-linked chromosome

Answer 34

hereditary disease

Question 35

What is the initial intervention for the treatment of hyperbilirubinemia

Answer 35

phototherapy

Question 36

The component of the blood that carries antibodies and nutrients to tissues and carries away waste is

Answer 36

plasma

Question 37

Which of the following is a disorder that results in the destruction of platelets

Answer 37

idiopathic thrombocytopenia purpura

Question 38

Which anemia develops as a result of folic acid deficiency

Answer 38

macrocytic

Question 39

The primary organ responsible for the production of ITP platelet antibodies is the

Answer 39

spleen

Question 40

Which clinical finding is associated with hyperbilirubinemia

Answer 40

jaundice

Question 41

The characteristic symptom that may present after exposure to Salmonella typhi is

Answer 41

persistant fever as high as 103-104 degrees F

Question 42

How long is the half-life of blood

Answer 42

30 days

Question 43

The extrinsic pathway of the clotting cascade is triggered by

Answer 43

tissue factor

Question 44

Which one of the following statements is true about sickle cell anemia

Answer 44

repeated episodes of sickling causes the cells to become irreversibly sickled

Question 45

Which pathway of the clotting cascade involves a tissue factor that is released by damaged cells

Answer 45

extrinsic pathway

Question 46

The most common caused of mortality in patients with ITP is

Answer 46

intracranial hemorrhage

Question 47

B-lymphocytes are produced in the

Answer 47

bone marrow

Question 48

The pathways involved in the clotting cascade and is triggered by blood coming in contact with collagen fibers is

Answer 48

the intrinsic pathway

Question 49

What is the final enzyme of the clotting cascade that produces fibrin

Answer 49

thrombin

Question 50

The intrinsic pathway in the clotting cascade involves the blood coming in contact with

Answer 50

collagen fibers

Question 51

The majority of absorbed iron in the small intestine is derived from

Answer 51

heme iron

Question 52

Hemolytic anemia occurs as a result of

Answer 52

excessive destruction of red blood cells