Hematology Flashcards Preview

USMLE Step 3 MTB > Hematology > Flashcards

Flashcards in Hematology Deck (268)
Loading flashcards...
1

all forms of anemia lead to

fatigue/loss of energy

2

pt with severe anemia will have

SOB, lightheadedness, or confusion

3

diseases with similar presentations to anemia:

- hypoxia
- CO poisoning
- methemoglobinemia
- ischemic heart disease

4

craving for ice or dirt, think

anemia, PICA

5

physical exam findings on anemic patient

- pallor
- flow murmur
- pale conjunctiva

6

physical exam findings in hemolytic anemia

- Jaundice
- scleral icterus

7

in severe anemia, what is needed to exclude ischemia?

EKG

8

best INITIAL test for anemia

CBC with peripheral smear

9

additional initial tests for anemia

- reticulocyte count
- haptoglobin
- LDH
- total and direct bilirubin
- TSH and free T4
- B12/folate levels
- iron studies
- UA w/ microanalysis

10

categorization of anemia is based on

MCV (mean corpuscular volume)

11

what value may indicate if there's a problem with the synthesis of Hb?

MCHC (mean corpuscular hemoglobin concentration)

12

anemia categorized based on MCV is as follows:

- microcytic
- macrocytic
- normocytic

13

based on MCHC anemia can be further categorized as follows:

- hypochromic
- hyperchromic
- normochromic

14

- blood loss
- THROMBOCYTOSIS

what is the diagnosis?

Iron Deficiency Anemia

15

- RA
- ESRD
- any chronic infectious, inflammatory, or connective tissue disease

what is the diagnosis?

Anemia of Chronic dz

16

- very small MCV w/ few or no symptoms
- TARGET cells; normal iron studies

what is the diagnosis?

thalassemia

17

- alcoholic
- INH
- lead exposure

what is the diagnosis?

sideroblastic anemia

18

best INITIAL test for IDA, ACD, thalassemia, or sideroblastic anemia

iron studies

19

results of iron studies in Iron def. anemia

- low ferritin
- high TIBC (total iron binding capacity)
- low iron
- low iron saturation
- elevated RDW (red cell distribution width)

20

results of iron studies in ACD

- HIGH ferritin (acute phase reactant)
- low TIBC (total iron binding capacity)
- low iron
- normal or low iron saturation

21

results of iron studies in thalassemia

NORMAL

22

results of iron studies in sideroblastic anemia

HIGH IRON

23

MOST ACCURATE test for IDA

bone marrow biopsy (don't do this on CCS exam)

24

MOST ACCURATE test for thalassemia

Hb electrophoresis

(beta: elevated HbA2, and HbF)
(alpha: normal)

25

MOST ACCURATE test for sideroblastic anemia

Prussian blue stain

26

best INITIAL treatment for IDA

ferrous sulfate PO

27

best INITIAL treatment for ACD

correct underlying cause

28

best INITIAL treatment for thalassemia

no treatment for trait

29

best INITIAL treatment for sideroblastic anemia

minor: pyridoxine (vitamin B6)
major: remove toxin exposure

30

MOST ACCURATE test for ALPHA thalassemia

DNA sequencing and not electrophoresis