Hemeonc/pain drugs for final Flashcards
(5 cards)
Class:
Generic: Ibuprofen
Action:
Uses:
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Adverse Effects:
Class: NSAID (Non-steroidal anti-inflammatory)
Generic: Ibuprofen
Action: Inhibits cyclooxygenase enzymes (COX-1 and COX-2)
Uses: Pain (analgesic), fever (antipyretic), inflammation, dysmenorrhea
Precautions: Risk of GI bleeding, renal impairment, Stevens-Johnson Syndrome
Adverse Effects: GI distress/ulcers, tinnitus, dizziness, headache, hives in blood vessels
Class:
Generic: Acetaminophen (Tylenol)
Action:
Uses:
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Adverse Effects:
Class: Non-narcotic analgesic
Generic: Acetaminophen (Tylenol)
Action: Central analgesic and antipyretic; inhibits prostaglandin synthesis in CNS
Uses: Mild pain, fever
Precautions: Do not exceed 4g/day (2g/day if liver compromised); adult NTE >10 days, child NTE >5 days
Adverse Effects: Hepatotoxicity, hepatic necrosis
Class:
Generic: Morphine
Action:
Uses:
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Antidote:
Class: Opioid Analgesic
Generic: Morphine
Action: Modulates pain perception in the CNS
Uses: Severe pain, anxiety relief, cough suppression
Precautions: Lowers respiratory reserve; monitor in opioid-naïve patients
Adverse Effects: Respiratory depression, opioid-induced constipation, orthostatic hypotension
Antidote: Naloxone (Narcan®)
Class:
Generic: Methadone
Action:
Uses:
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Class: Opioid Analgesic
Generic: Methadone
Action: Similar to morphine; long-acting opioid agonist
Uses: Treatment for opioid dependence/addiction
Precautions: Prolongs QT interval; longer half-life
Adverse Effects: Not commonly tested—know QT prolongation risk
Class:
Generic: Naloxone (Narcan®)
Action:
Uses:
Precautions:
Adverse Effects:
Class: Opioid Antagonist
Generic: Naloxone (Narcan®)
Action: Blocks opioid receptors
Uses: Reversal of opioid overdose
Precautions: May trigger acute withdrawal in dependent individuals
Adverse Effects: Loss of pain relief; agitation in opioid-dependent patients
