Quiz 5

Question 1

Drug: Ferrous Sulfate
Class:
Action:
Uses:
Precautions:
Adverse Effects:
Antidote:

Answer 1

Drug: Ferrous Sulfate
Class: Hematinic
Action: Increases production of normal hemoglobin
Uses: Iron deficiency anemia, blood loss
Precautions: Use a straw for oral form; Z-track for IM
Adverse Effects: Constipation, black tarry stools, tissue staining
Antidote: Deferoxamine

Question 2

Drug: Epoetin Alfa
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 2

Drug: Epoetin Alfa
Class: Hematopoietic Growth Factor
Action: Increases RBCs
Uses: Anemia, blood loss, bone marrow suppression
Precautions: IV or Sub-Q administration
Adverse Effects: Iron deficiency (due to increased RBC production)

Question 3

Drug: Filgrastim
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 3

Drug: Filgrastim
Class: Hematopoietic Growth Factor
Action: Increases WBCs
Uses: Neutropenia in chemotherapy patients
Precautions: IV or Sub-Q
Adverse Effects: Bone pain

Question 4

Drug: Oprelvekin
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 4

Drug: Oprelvekin
Class: Thrombopoietic Growth Factor
Action: Increases platelets
Uses: Thrombocytopenia
Precautions: Sub-Q only
Adverse Effects: Fluid retention, cardiac dysrhythmias

Question 5

Drug: Methotrexate
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 5

Drug: Methotrexate
Class: Antimetabolite
Action: Blocks folic acid activation, disrupts DNA
Uses: Rheumatoid arthritis, Crohn’s disease
Precautions: Take vitamin B for tingling/numbness
Adverse Effects: Bone marrow suppression

Question 6

Drug: Vincristine
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 6

Drug: Vincristine
Class: Mitotic Inhibitor
Action: Disrupts microtubules during mitosis
Uses: Cancer (combo therapy)
Precautions: Vesicant—tissue destruction risk
Adverse Effects: Alopecia, peripheral neuropathy

Question 7

Drug: Cyclophosphamide
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 7

Drug: Cyclophosphamide
Class: Alkylating Agent
Action: Alkalizes DNA to stop replication
Uses: Blood cancers, Hodgkin’s/non-Hodgkin’s
Precautions: Delayed onset of adverse effects
Adverse Effects: Alopecia

Question 8

Drug: Doxorubicin
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 8

Drug: Doxorubicin
Class: Antitumor Antibiotic
Action: Distorts DNA structure
Uses: Breast cancer
Precautions: Dose-dependent toxicity
Adverse Effects: Cardiotoxicity (RED drug), EKG changes

Question 8

Drug: Cisplatin
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 8

Drug: Cisplatin
Class: Platinum Compound
Action: Nonspecific cell cycle inhibitor
Uses: Testicular, ovarian, bladder cancer
Precautions: High doses → kidney injury
Adverse Effects: Bone marrow suppression

Question 9

Drug: Tamoxifen
Class:
Action:
Uses:
Precaution:
Adverse Effects:

Answer 9

Drug: Tamoxifen
Class: Breast Anticancer Hormone
Action: Blocks estrogen receptor activation
Uses: Breast cancer
Precaution: endometrial cancer
Adverse Effects: Hot flashes, fluid retention

Question 10

Drug: Isoflurane
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 10

Drug: Isoflurane
Class: Inhaled Anesthetic (Volatile Liquid)
Action: Excreted by exhalation
Uses: General anesthesia
Precautions: Requires intubation and ventilator
Adverse Effects: Respiratory depression

Question 11

Drug: Propofol
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 11

Drug: Propofol
Class: Sedative-Hypnotic
Action: Induces sleep; no pain relief
Uses: Sedation (e.g., celebs, ICU)
Precautions: Lipid-based; needs ventilatory support
Adverse Effects: Respiratory depression, infection risk

Question 12

Drug: Morphine
Class:
Action:
Uses:
Precautions:
Adverse Effects:
Antidote:

Answer 12

Drug: Morphine
Class: Opioid Analgesic
Action: Modulates pain in brain/spinal cord
Uses: Pain, anxiety, cough suppression
Precautions: Lowers respiratory reserve
Adverse Effects: Respiratory depression, constipation, orthostatic hypotension
Antidote: Naloxone (Narcan)

Question 12

Drug: Methadone
Class:
Action:
Uses:
Precautions:

Answer 12

Drug: Methadone
Class: Opioid Analgesic
Action: Similar to morphine
Uses: Opioid addiction
Precautions: Long half-life, prolongs QT interval

Question 13

Drug: Naloxone (Narcan)
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 13

Drug: Naloxone (Narcan)
Class: Opioid Antagonist
Action: Blocks opioids
Uses: Reverses opioid overdose
Precautions: Given IV, IM, or Sub-Q
Adverse Effects: Withdrawal symptoms, loss of pain relief

Question 14

Drug: Oxycodone
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 14

Drug: Oxycodone
Class: Opioid Agonist
Action: Pain relief, euphoria
Uses: Pain management
Precautions: High abuse potential
Adverse Effects: GI distress, pinpoint pupils, respiratory depression

Question 15

Drug: Naltrexone (Revia)
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 15

Drug: Naltrexone (Revia)
Class: Pure Opioid Antagonist
Action: Blocks euphoria/pleasure
Uses: Alcohol and opioid dependence
Precautions: Long half-life
Adverse Effects: Nausea, headache, anxiety, sedation

Question 16

Drug: Alcohol
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 16

Drug: Alcohol
Class: CNS Depressant
Action: Enhances dopamine; CNS depression
Uses: Social/euphoric effects
Precautions: Risk with other depressants (e.g., Ativan)
Adverse Effects: Wernicke’s encephalopathy, Korsakoff’s psychosis, liver/heart damage

Question 17

Drug: Disulfiram
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 17

Drug: Disulfiram
Class: Alcohol Abstinence Aid
Action: Causes unpleasant effects when alcohol is consumed
Uses: Maintain alcohol abstinence
Precautions: Avoid all forms of alcohol
Adverse Effects: Nausea, headache, flushing, weakness

Question 18

Drug: Cocaine
Class:
Action:
Uses:
Precautions:
Adverse Effects:

Answer 18

Drug: Cocaine
Class: Psychostimulant
Action: Blocks dopamine reuptake
Uses: Euphoria, local anesthesia
Precautions: Overdose risk
Adverse Effects: Hyperthermia, dysrhythmias, stroke, MI