HEMOSTASIS DISEASES

Question 1

what are the vitamin K dependent factors?

Answer 1

2, 7,9 10, and protein C

Question 2

what are the three particular types of bleeding tendencies?

Answer 2

Vitamin K Deficiency, Hemophilia, Thrombocytopenia (platelet deficiency)

Question 3

an infection and inflammation in the liver

Answer 3

hepatitis

Question 4

there is a scarring in your liver

Answer 4

cirrhosis

Question 5

Decreased formation of Vitamin K dependent factors

Answer 5

vitamin K

Question 6

decrease of vitamin K causes?

Answer 6

excessive bleeding

Question 7

where is vitamin K continually synthesized?

Answer 7

in the intestinal tract by bacteria

Question 8

a disease where vitamin K deficiency occurs
as a result of poor absorption of fats from the GIT

Answer 8

GI disease

Question 9

One of the most prevalent causes of Vitamin K deficiency-

Answer 9

failure of the liver to secrete bile

Question 10

is injected into surgical patients with liver disease or with obstructed bile ducts

Answer 10

Vitamin K

Question 11

is the presence of stones in the common bile duct or biliary tree

Answer 11

Choledocholithiasis

Question 12

Bleeding disease that occurs almost exclusively in males

Answer 12

Hemophilia

Question 13

a disease where 85% abnormality or deficiency of Factor VIII

Answer 13

Hemophilia A or classic hemophilia

Question 14

a disease where 15% deficiency of Factor IX

Answer 14

Hemophilia B

Question 15

what are the 2 active components of factor VIII?

Answer 15

Large component and smaller componenet

Question 16

what does the large component in factor VIII cause?

Answer 16

Von Willebran Disease

Question 17

one of the two components of factor VIII where it is the deficiency cause hemophilia

Answer 17

Smaller component

Question 18

Presence of very low number of platelets

Answer 18

Thrombocytopenia

Question 19

The patient has a tendency to bleed usually from many
small venules or capillaries that’s why you have small punctate hemorrhages or small purplish blotches, or we call that ________

Answer 19

purpura

Question 20

n the case of patient presenting dark purplish blotches or there is purpura ,so we call that _______

Answer 20

Thrombocytopenic purpura

Question 21

hemophilia occurs in ______ vessels while thrombocytopenia occurs in _________ vessels.

Answer 21

Large, small

Question 22

what do you call where purpura a larger in cases?

Answer 22

ecchymosis

Question 23

it is the bleed of usually from many small venules or capillaries

Answer 23

small punctuate hemorrages

Question 24

Bleeding will not occur until the number of platelets falls ____________ u/L

Answer 24

below 50,000

Question 25

specific Ab have formed and react against platelets to destroy them.

Answer 25

Idiopathic thrombocytopenic

Question 26

abnormal clot that develops in a blood vessel; immobile

Answer 26

Thrombus

Question 27

clot that breaks away from its attachment cause the clot to flow with the blood; mobile

Answer 27

Emboli

Question 28

what are the causes of Thromboembolic conditions?

Answer 28

Roughened endothelial surface of a vessel and when it flows slowly

Question 29

Immobility of patients confined to bed plus the practice of propping the knees with pillows

Answer 29

Femoral Venous Thrombosis

Question 30

Patients confined to bed such as those in the ICU or bed- ridden patients have the tendency to form ________

Answer 30

intravascular clotting

Question 31

heart going to the lungs that would now cause blockage this refers to the condition

Answer 31

‘Pulmonary embolism’

Question 32

other term of consumptive coagulopathy

Answer 32

disseminated intravascular dissemination

Question 33

Consumption of procoagulants = _____________

Answer 33

consumptive coagulopathy

Question 34

what is the quantity of heparin injected in the body?

Answer 34

0.5-1 mg/kg

Question 35

how many hours does the heparin last?

Answer 35

1.5-4hours

Question 36

what are the active component that fall during warfarin?

Answer 36

active prothrombin, Factor VII, IX, and X

Question 37

what are the chemicals used in the prevention of blood coagulation outside the body

Answer 37

heparin, oxalate and citrat

Question 38

a prevention of blood coagulation where it is used in surgical procedures in which the blood must be passed through a heart-lung machine or artificial kidney machine

Answer 38

heparin

Question 39

a prevention of blood coagulation where precipitation of calcium oxalate from the plasma and thereby decreases the ionic calcium level

Answer 39

oxalate

Question 40

what is the color of the top of the tube with oxalate?

Answer 40

Gray top tube

Question 41

Prevent the initiation of the coagulation system

Answer 41

oxalate

Question 42

one of the chemicals for the prevention of blood coagulation where it Prevent the initiation of the coagulation system

Answer 42

oxalate

Question 43

lack of clotting factors prolongs?

Answer 43

bleeding time

Question 44

a method where you puncture the drop of blood should be placed in the filter paper and it will be timed. So, the Normal value is 1-6 minutes.

Answer 44

IVY METHOD

Question 45

normal time value of clotting in IVY method?

Answer 45

1-6 minutes

Question 46

what do you call the time required for coagulation to take place?

Answer 46

prothrombin time

Question 47

what is the normal prothrombin time?

Answer 47

12 secs

Question 48

puncture the drop of blood should be placed in the filter paper and it will be timed. So, the Normal value is 1-6 minutes.

Answer 48

IVY METHOD

Question 49

INR meaning?

Answer 49

international Normalized Ratio

Question 50

what is the normal INR range?, Risk of high bleeding? clotting ratio of INR? of the parathrombin

Answer 50

0.9-1.3 , 4-5 , 0.5

Question 51

ndicates the activity of the tissue factor with a standardized sample

Answer 51

internal sensitivity index

Question 52

the internal sensitivity index varies between ?

Answer 52

1-2

Question 53

normal value of clotting time?

Answer 53

6-10 minutes