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Flashcards in Hepatitis Deck (23):
1

How is Hep A transmitted?

Fecal-oral

2

How is Hep B transmitted?

Blood - IVDU and needles
Sexual
Mom --> fetus

3

How is Hep C transmitted?

Blood - IVDU and needles
Sex - more unlikely

4

How is Hep D transmitted?

Blood
Same as B since present together

5

How is E transmitted?

Fecal-oral

6

What does high transaminases (ALT/AST) indicate?

Hepato-cellular injury, necrosis, death

7

What is the likely outcome of Hep A infection in adults?

Fully recovery
No chronic damage or cancer

8

What is the likely disease process and outcome of Hep A infection in kids?

Less severe disease - likely asymptomatic

9

What is the disease outcome of Hep B infection in adults?

Highest chance for full recovery
Chance of:
- Chronic hepatitis
- Higher risk of fulminant (sudden onsent) hepatitis

10

What complication is associated with Hep B in kids?

Higher risk of chronic hepatitis
But again, disease is likely to be less severe in kids

11

What is the Hep A vaccine?

Killed virus

12

What is the Hep B vaccine?

Recombinant surface antigen

13

Which has the highest risk of transmission via needle stick: HIV, Hep B, or Hep C?

Hep B!!

14

What do you give for Hep B prophylaxis?

Hyper immune gloublin + vaccine

15

Hep C prophylaxis

IFNa if acute infection develops
Otherwise monitor

16

Causes of cirrhosis

Alcohol
Hep B & C
Congenital
Toxins/meds

17

Treat Hep B

RT inhibitors: tenofovir
Pegylated IFNa

18

Treat Hep C

IFNa + ribavirin + protease inhibitor (telaprevir or boceprevir)

19

What stage of infection is Hep C Ab neg but RNA present?

Acute

20

What stage of infection is Hep Ab neg and RNA neg?

Not infected!!

21

What stage of infection is Hep C Ab + RNA +?

Active chronic?

22

What stage of infection is Hep C Ab+ RNA -?

Previous/resolved/not ongoing Hep C infection

23

Which Hep C genotype is most common throughout the US?

Type 1a