Flashcards in L77 Deck (11):
Ebola's non-human reservoir
Will Ebola be eradicated?
No - can't kill or immunize all the bats
P2P - blood highest risk
Air - low risk
How do you make Ebola self-limiting?
What cells does Ebola initially infect?
When do infected people begin to be able to actively transmit Ebola?
Until symptoms, you can't even find the virus in the blood by PCR
What dets worse prognosis with Ebola
Higher viral load
What kind of disease is Ebola? What is the first symptom? What is the gimme symptom?
Viral hemorrhagic fever
Fever = most common
Bleeding anywhere = hallmark
- Not common
- Happens in late stages if at all
- Not really the life threatening aspect
Explain IFN therapy.
Infected cells naturally produce IFN to induce an anti-viral state in neighboring cells to prevent infection
If you give IFN as a med - you'd make host cells inhospitable to infection
IFN mechanism of preventing infection
Viral mRNA degradation
X ribosome assembly