Histology of non-pregnant female Flashcards

1
Q

Label the female repro system

A
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2
Q

What is the function of the ovaries?

A

production of female gametes/oocytes/eggs
Production of female sex steroids

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3
Q

Describe the anatomy of the ovaries

A

Cortex: outer parenchymatous zone containing follicle and corpus luteums
Medulla: inner vascular zone
Stroma: spindle-shaped cells that surround ovarian follicles

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4
Q

Label the ovarian histology

A
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5
Q

Describe the formation of an ovarian follicle

A

Follicle composed of an oocyte surrounded by specialised epithelial cells (granulosa/cumulus)
During follicular development, epithelial cells become surrounded by theca cells (Specialised stroma) and a fluid-filled cavity develops among epithelial cells
These layers are separated by a basement membrane

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6
Q

Describe the structure of a primordial follicle

A

Least developed and most numerous
Primary oocyte surrounded by simple squamous epithelial granulosa cells

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7
Q

Describe the structure of a primary follicle

A

The first developmental stage
primary oocyte surrounded by simple cuboidal epithelila granulosa cells

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8
Q

Describe the structure of a secondary follicle

A

Granulosa cells proliferate and form a stratified epithelium (multiple layers of granulosa cells)

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9
Q

Describe the structure of an early antral follicle

A

Characterised by a fluid-containing cavity (the antrum)
Theca cells differentiate into 2 layers (interna and externa)

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10
Q

Describe the structure of the antral/tertiary/Graafian follicle

A

The granulosa cells form a thickened mound (cumulus oophorus) which projects into the antrum

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11
Q

What stage of follicle development is this?

A

Primordial

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12
Q

What stage of follicle development is this?

A

Primary follicle

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13
Q

What stage of follicle development is this?

A

Secondary follicle

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14
Q

What stage of follicle development is this?

A

Early antral follicle

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15
Q

What stage of follicle development is this?

A

Antral/tertiary/Graafian follicle

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16
Q

Describe the formation of corpus luteum

A

At ovulation, the follicular walls, composed of the granulosa and thecal cells collapses
Theca cells become small luteal cells
Granulosa cells become large luteal cells
Basement membrane breaks down, tissue is remodelled, vessels increase and is transformed into the CL

Early stage = corpus haemorrhagicum

17
Q

Label the histology of the CL

A
18
Q

What is the corpus albicans

A

Scar tissue on the ovary of a previous CL

19
Q

Label this ovarian cross section

A
20
Q

Label this antral follicle cross section

A
21
Q

What are the layers of the oviduct wall?

A

Serosa (peritoneum) - outer
Muscularis
Mucosa - inner

22
Q

Describe the histology of the oviduct

A

Mucosa projects into lumen as longitudinal folds
BVs supply the tubes via the mesosalpinx
Mucosa is lined by simple or pseudostratified columnar epithelum with ciliated and secretory cells

23
Q

Label this oviduct histology

A
24
Q

Label this oviduct histology

A
25
Q

How do you differentiate between the ampulla and isthmus of the oviduct?

A

Ampulla - longer, thin walled, primary, secondary and tertiary mucosal folds
Isthmus - shorter, thicker walled, fewer longitudinal mucosal folds

26
Q

Identify the different parts of the oviduct

A

Ampulla - LEFT
Isthmus - RIGHT

27
Q

What are the 3 segements of the uterus?

A

Horns - cornua
Body - corpus
Neck - cervix

28
Q

What are the 3 layers of the uterine wall and their functions?

A

Inner - Endometrium - mucosa - secretory and support embryo/pregnancy
Myometrium - muscularis - contractile for parturition
Outer - Perimetrium - serosa - protection

29
Q

Label this uterine histology

A
30
Q

Label this uterine histology

A