Spermatogenesis and testicular function Flashcards by Leah Stevenart | Brainscape

Q

Describe the stages of spermatogenesis

A

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Q

What are the 3 phases of spermatogenesis?

A

Proliferation - mitotic divisions
Meiosis - crossing over ensures genetic heterogenecity, haploid spermatids produced
Differentiation - formation of cell capable of fertilisation

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Q

Describe the proliferation phase of spermatogenesis

A

A-spermatogonia:
- mitotic division from A1 to A4
- pool of stem cells maintained
I-spermatagonia:
- intermediate
B-spermatagonia:
- mitotic division to primary spermatocytes
- meiosis

The spermatogonia are connected by intercellular bridges so they divide in groups
Some spermatogonia cells are removed from the I and B stages as a means of replenishing the pool of A1 spermatogonia to ensure continuous spermatogenesis

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Q

What are the phases of spermatid differentiation?

A

Golgi phase
Cap phase
Acrosomal phase
Maturation phase

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Q

Describe the golgi phase of spermatid differentiation

A

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Q

Describe the cap phase of spermatid differentiation

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Q

Describe the acrosomal phase of spermatid differentiation

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Q

Describe the maturation phase of spermatid differentiation

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Q

What are the features of the spermatozoa head?

A

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Q

What are the features of the spermatozoa tail?

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Q

What generations of spermatozoa cells are found at cross section 1 of the seminiferous tubules?

A

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Q

What generations of cells are found at stage 4 of the seminiferous tubule?

A

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Q

What generations of cells are found at stage 8 of the seminiferous tubule

A

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Q

How many cycles does spermatogonia take?

A

4.5

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Q

Label the patterns of GnRH, LH and FSH secretion throughout the day in males

A

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Q

What is the role of LH in males?

A

Binds to receptors on Leydig cells
Leydig cells produce testosterone

Q

What is the function of FSH?

A

Binds to receptors on sertoli cell
Sertoli cells convert testosterone to oestreadiol and produce inhibin

Q

How is the HPT axis controlled?

A

Testosterone inhibits GnRH -> pulsatile changes
Dihydrotestosterone also has -ve feedback effect on hypothalamus
Inhibin inhibits FSH secretion

Q

A