Mechanisms of incontinence Flashcards

1
Q

What is incontinence?

A

the lack of voluntary control of excretory functions

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2
Q

What clinical syndromes are disorders of micturition?

A

Inappropriate voiding
Inadequate voiding with urine overflow => dribbling
Increased urination frequency
Reduced bladder capacity
Incomplete voiding

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3
Q

Define enuresis

A

unconscious leakage of urine during sleep

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4
Q

Describe the clinical examination for disorders with micturition

A

History of voiding
Bladder size - palpation
Urethral sphincter tone - squeeze bladder to check for leakage
Integrity of detrusor/micturition reflex - squeeze bladder to stimulate urination
Perineal reflex - check for ‘winking’ around perineal region to check sacral nerve function
Full neurological assessment

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5
Q

What is the result of an upper motor neurone lesion?

A

spastic paralysis
hyper/normoreflexia
Slow muscle wastage

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6
Q

What is the result of a lower motor neurone lesion?

A

Flaccid paralysis
Hypo/areflexia
Rapid muscle wastage

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7
Q

Where are lower motor neurone lesions of the bladder?

A

Sacral spinal segment damage
Pelvic plexus

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8
Q

What is the results of lower motor neurones of the bladder?

A

Absent voluntary micturition
Atonic bladder
Atonic urethral sphincters
Absent detrusor reflex
Concurrent reduced perineal reflex and anal tone
Bladder flaccid and easily expressed

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9
Q

Where are upper motor neurone lesions of the bladder?

A

High spinal cord
brain dysfunction

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10
Q

What is the effect of an upper motor neurone lesion on the bladder

A

Absent voluntary micturition
Increased urethral tone
high volume urinary retention
Development of automatic bladder - no voluntary control

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11
Q

What are the anatomical disorders causing incontinence?

A

Ectopic ureter:
- Congenital malformation
- ureters enter directly into urethra
Acquired abnormalities of lower urinary tract:
- neoplasia
- calculi (bladder stones block urethra)
- Trauma

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12
Q

Describe the clinical findings and treatment of calculi/bladder stones blocking the urethra

A

Large bladder
does not release urine when squeezed
Need to relieve pressure via cystocentesis or catheter

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13
Q

Describe the effect of trauma on the lower urinary tract

A

Cannot urinate
Urine goes into abdomen
Bladder will be normal size
Will not be trying to urinate
Fluid in abdomen => very ill

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14
Q

Describe disorders of bladder function

A

Functional outflow obstruction - reflex dyssynergia
Initiation of detrusor reflex with reflex contraction of urethral sphincter - tries to urinate but cannot
Sphincter mechanism incompetence
Secondary detrusor muscle atony - stretch related injury => loss of contractility
Stretch injury
Urge incontinence:
- micturition reflex at low volume
- bladder mucosa irritation

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15
Q

Describe sphincter mechanism incontinence

A

Normal micturition reflex but sphincter too loss in between micturition reflexes => urine leaks when there is increased abdominal pressure e.g., when excited

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16
Q

Describe the signalment of sphincter mechanism incontinence

A

More common in female due to short urethra
More common in large/giant breeds
More common in spayed female (hormonal changes)

17
Q

What are the treatment strategies for sphincter mechanism incompetance?

A

alpha adrenergic agonists e.g., phenylpropanolamine)
Oestrogens
Surgery - culposuspension:
- band around bladder and pulled up into abdomen stretches urethra
- urethra stretched => increased tone and decreased diameter

18
Q

How does tail stretch injuries in cats cause bladder atony?

A

Sacral nerves stretch and pulled out of spinal cord (avulsion) => lost function