Histology of stomach and intestines Flashcards Preview

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Flashcards in Histology of stomach and intestines Deck (16):

three regions of stomach glands and differences b/w them

cardiac and pyloric have fewer parietal, chief and enteroendocrine cells than fundic area. They have more mucous cells. Deeper pits (greater pit:gland ratio)


five types of cells in stomach and where you find them

surface mucous: on surface or in gastric pits. Neck mucous: neck of gastric glands. Parietal: in gastric glands, secrete HCl and IF. Chief: basal half of glands, secrete pepsinogen. Enteroendocrine: release hormones from basal side which modulate digestion, scattered.


layers of muscle in stomach

inner oblique, middle circular, outer longitudinal


unique features of parietal cells

lots of mitochondria, secretory canaliculus


appearance of chief cells on stain? mucous? parietal?

darker staining. washed out. pink and puffy relative to neighbors


three surface area increasing features of small bowel and what they're made of

plicae circularis (submucosa and mucosa), villi (mucosa), microvilli (plasma membrane)


where do you find stem cells in stomach and intestine

in the neck of gastric glands and crypts of Lieberkuhn


process of lipid digestion and absorption

Emulsified by bile salts and lecithin, broken down by pancreatic lipase. Micelles diffuse into cell, are made into triglycerides and packaged into chylomicrons which are discharged into intercellular space and taken up by lacteals or capillaries


process of protein digestion and absorption

pepsin cleaves proteins into polypeptides. Pancreatic trypsin, chymotrypsin and carboxypeptidase produce free AAs. Taken up by active transport


process of carbohydrate digestion and absorption

salivary amylase, pancreatic amylase. Brush border sucrase, maltase, lactase and aminopeptidase. Glucose and galactose taken up via Na dependent active transport


Paneth cells

in base of crypt. secrete antibacterial lysozyme


Role of CCK

most important in duodenum. Signals pancreas and gallbladder to do everything.


M (microfold) cells

take up microorganisms (and IgA?) via transcytosis. Overly peyer's patches


Brunner's glands: where?

duodenum in submucosa


where do you see peyer's patches?

ileum below the epithelium


three characteristics of large intestine histology

no villi, abundant goblet cells, teniae coli