Flashcards in GI motility disorders Deck (10):
histopathology of achalasia
degeneration of myenteric NO (inhibitory) neurons due to inflammation
what can mimic GI dysmotility both radiographically and manometrically
mechanical obstruction (must rule out!)
three main causes of secondary achalasia
psuedoachalasia (Cancer associated), post fundoplication, Chagas
Diabetic gastroparesis: what type of neuropathy? What happens?
autonomic (vagal). Gastric body and antral hypomotility and pylorospasm result in prolongation of emptying times
two motility patterns of small bowel and describe them
Fed pattern- segmenation. Fasting pattern- MMC
three phases of MMC
Phase 1- motor inactivity. Phase 2- intermittent, non propagating contractions. Phase 3- burst of contractions from duodenum to distal ileum
Scleroderma: what type of neuropathy? Where in GI tract? Most common location? What happens when it occurs in small bowel?
myopathic. Any part. Esophageal dysmotility. Absent contractile activity leads to dilation with stacked coin appearance and diverticulae
two main causes of intestinal pseudo-obstruction
post operative ileus. Scleroderma
Ogilvie's Syndrome: what type of neuropathy? when does it occur? Where does it occur? What happens?
autonomic. post-op. hindgut. Colonic distention in absence of mechanical obstruction