HIV meds

Question 1

Fusion/entry inhibitors

Answer 1

Prototype: Enfuvirtide (SubQ)

Purpose: Decreases and limits spread by blocking HIV from CD4 cell

Question 2

CCR5 Antagonists

Answer 2

Prototype: Maraviroc (PO)

Purpose: Prevents HIV from entering lymphocytes, binding to CCR5 on cell membranes

Question 3

NRTIs

Answer 3

Prototype: Zidovudine (PO, IV)

Purpose: Reduces HIV manifestations by inhibiting DNA synthesis thus viral replication

Question 4

NNRTIs

Answer 4

Prototypes: Delavirdine and Efavirenz (PO)

Purpose: Act directly on reverse transcriptase to stop HIV replication

Question 5

Protease Inhibitors

Answer 5

Prototype: Ritonavir (PO)

Purpose: Act against HIV-1 and 2 to alter and inactivate the virus by inhibiting enzymes needed for replication

Question 6

Integrase Inhibitors (INSTIs)

Answer 6

Prototype: Raltegravir (PO)

Purpose: Interferes w/ enzyme integrase to prevent HIV replication within the cell