HTN Day 2 Flashcards Preview

Pharm II MHM - FINAL > HTN Day 2 > Flashcards

Flashcards in HTN Day 2 Deck (15):
1

Which beta blockers are cardioselective?

AMEBBA
Atenolol, Metoprolol, Esmolol, Bisprolol, Betaxalol, Acebutolol

2

What are the ADEs of beta blockers?

"Beta blocker blues" = tired, depressed, sexual dysfunction

3

Which ADEs of beta blockers will resolve with time and which will not?

-Fatigue/depression should resolve with time
-Sexual dysfunction will not resolve with time

4

What happens when beta blocker doses are skipped or the drug is stopped suddenly?

Rebound HTN

5

How are beta blockers used for HTN?

They are NOT 1st line
Reserved for patients with cardiac history (MI, HF, CAD)

6

What are the major CIs to beta blockers?

Asthma/COPD - use selective agents only
DM - masks hypoglycemia symptoms (except sweating!)

7

What should DM patients on beta blockers be aware of?

B blockers mask the symptoms of hypoglycemia EXCEPT sweating

8

Unique feature(s) of sotalol

-Beta blocker but NOT used for HTN
-Only used as an anti-arrhythmic agent

9

What are the mixed alpha and beta blockers?

Carvedilol
Labetalol

10

Which beta blocker is safe for use in pregnancy?

Labetalol

11

Which beta blockers have ISA?

CAPP
Carteolol, Acebutolol, Penbutolol, Pindolol

12

Which beta blockers have non-specific activity?

Nadolol, propranolol, timolol

13

Features of propranolol

-Migraine prophylaxis (lipophilic, can cross BBB)
-Used for tx of "stage fright" anxiety

14

What are examples of alpha 1 blockers?

Prazosin, doxazosin, tamsulosin, alfuzosin

15

MOA of alpha 1 blockers

-Inhibits peripheral alpha-1 receptors
-Causes vasodilation