Immunology of Pregnancy Flashcards
(7 cards)
1
Q
What can mast cells do?
A
Help fine tune the development of corneas and vascularisation
2
Q
Can mast cells cause scars during foetal development?
A
Yes, at day E18 in mice
3
Q
Can you lack mast cells?
A
No
4
Q
What happens if you knock out mast cells in mice?
A
All mice die shortly after birth
5
Q
Why do mast knockout mice die shortly after birth?
A
Breathing difficulties, inability to suckle and skin homeostasis
6
Q
Skin permeability and mast cell study?
A
If there are no mast cells skin becomes more permeable as it takes on more dye. This means these mice have increased water loss, and decreased weight
6
Q
What are mast cells?
A
Immune cells in the body found in connective tissues of the body
