IMMUNOSERO Flashcards

(46 cards)

1
Q

The study of all aspects of the immune system, including its structure and function.

A

Immunology

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2
Q

It deals with the response of an organism to antigenic challenge and its recognition of what is self and non-self.

A

Immunology

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3
Q

A division of immunology that specializes in the laboratory detection and measurement of antigens and antibodies.

A

Serology

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4
Q

The ability of an organism to resist a particular infection or toxin by the action of specific antibodies or sensitized white blood cells.

A

Immunity

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5
Q

a substance that is capable of stimulating an immune response

A

Antigens

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6
Q

a foreign agent that is not considered by the body as self.
Ex. bacteria, viruses, allergens

A

Antigens

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7
Q

proteins made by plasma cells in response to an antigen

A

ANTIBODIES

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8
Q

skin (epithelial cells), mucous membrane (sebum, saliva, tears, stomach acid, normal flora)

A

First line

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9
Q

consists of particular cells (monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells.) and soluble substances in the blood (complement, lysozyme, interferon). The inflammatory response enhances the activation of white blood cells.

A

Second line

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10
Q

direct fighters of foreign invaders and also produced cytokines, which are biological substances that help activate other parts of the immune system.

A

T-Lymphocytes

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11
Q

produce antibody molecules that can latch on and destroy invading viruses or bacteria.

A

B-Lymphocytes

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12
Q

memorize the characteristics of the antigen that activated their parent B cell during initial infection such that if the memory B cell later encounters the same antigen, it triggers an accelerated and robust secondary immune response. (vaccination)

A

B memory cells

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13
Q

forms a 3rd line defense that allows the body to recognize, remember, and respond to a specific stimulus, an antigen.

A

ADAPTIVE

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14
Q

can result from natural exposure in response to an infection (natural) or from an intentional vaccination with an antigen-bearing microorganisms (artificial)

A

ACTIVE

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15
Q

should stimulate the production of antibodies in a person with the disease

A

ACTIVE

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16
Q

a person is given antibodies to a disease rather than producing them through his or her own immune system.

A

PASSIVE

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17
Q

○ if organisms have penetrated the first line of defense.
○ nonspecific
○ this 2nd line of defense consists of particular cells (neutrophils, tse basophils, macrophages) and soluble substances in the blood (complement, lysozyme, interferon)
○ immune response
○ Inborn ( given to us at birth/ fertilization)
○ biologic

A

INNATE

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18
Q

is an impairment of the immune system

A

Immunodeficiency

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19
Q

when the immune system attacks the body’s healthy cells, tissues and organs.

A

autoimmune disease

20
Q

Plays an important role in the diagnosis of diseases using different tests.

A

Binding of antigen to a specific antibody

21
Q

are designed to detect the presence of either antigen or antibody in the unknown sample.

22
Q

To determine bacterial infections associated with persistent fever
Make use of bacterial antigens to detect the presence of antibodies.

A

● Bacterial
Agglutination tests

23
Q

To determine bacterial infections associated with persistent fever

A

Bacterial Agglutination tests

24
Q

Make use of bacterial antigens to detect the presence of antibodies.

A

Bacterial Agglutination tests

25
specific test for typhoid fever: - TYPHIDOT
Widal test
26
non-specific test for typhus fever
Weil-Felix test
27
diagnostic test for streptococcal infections
Antistreptolysin O (ASO)
28
non-specific test for syphilis
Rapid plasma Reagin (RPR)
29
specific test for syphilis
Treponema pallidum hemagglutination assay (TPHA) test
30
non-specific marker for inflammation/infection
C-Reactive protein (C-RP) test and C3c radioimmunodiffusionassay (RID) test
31
mimics your own antibodies - causes infecions
Tests for heterophile antibodies
32
(caused by Epstein-Barr virus)
Infectious mononucleosis [IM]
33
Presumptive method
Paul-Bunnel test
34
classical reference method for heterophile antibodies
Davidson Differential test
35
qualitative test that detects IM heterophile antibodies in the sample.
Monospot test
36
detects ß-human chorionic gonadotropin (ß-HCG) Could also detect cancer of cervix, testicular cancer, and other medical conditions.
● Pregnancy test
37
a fast-screening test that detects HIV-1 and HIV-2 antibodies in the specimen
HIV Tests
38
(ex.ELISA) screening
HIV rapid test
39
Western blot test
confirmatory
40
a rapid qualitative screening test for the detection of hepatitis B infection.
HBsAg rapid test
41
a rapid test designed to detect: ■ NS1 antigen ■ Antibodies (IgG and IgM)
Dengue duo test
42
detects presence of antinuclear antibodies (destroys your own RBC) associated with SLE
Systemic lupus erythematosus (SLE) latex test
43
Used to determine rheumatoid arthritis
Rheumatoid factor (RF) latex test
44
To determine compatibility in organ, tissue, and bone marrow transplantation To determine paternity To diagnose HLA-related disorders such as autoimmune diseases.
Human Leukocyte Antigen (HLA)
45
Ex. Rheumatoid arthritis, type 1 DM, Systemic lupus erythematosus (SLE), celiac disease, lymphoma.
Human Anaphy . Human Leukocyte
46
Ex. Rheumatoid arthritis, type 1 DM, Systemic lupus erythematosus (SLE), celiac disease, lymphoma.
Human Anaphy. Human Leukocyte