Immunosuppressant Drugs II Flashcards Preview

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Flashcards in Immunosuppressant Drugs II Deck (24)
1

What condition is Filgrastim used to treat?

Recovery of bone marrow (p.210)

2

What condition is Sargramostim used to treat?

Recovery of bone marrow (p.210)

3

What conditions is a-interferon used to treat?

Hepatitis B and C, Kaposi's sarcoma, leukemias, malignant melanoma (p.210)

4

What condition is b-interferon used to treat?

Multiple sclerosis (p.210)

5

What condition is y-interferon used to treat?

Chronic granulomatous disease (p.210)

6

What condition is Oprelvekin used to treat?

Thrombocytopenia (p.210)

7

What condition is Thrombopoietin used to treat?

Thrombocytopenia (p.210)

8

Name eight therapeutic antibodies.

1.) Muromonab-CD3 (OKT3); 2.) Digoxin Immune Fab; 3.) Infliximab; 4.) Adalimumab; 5.) Abciximab; 6.) Trastuzumab (Herceptin); 7.) Rituximab; 8.) Omalizumab (p.210)

9

What is the therapeutic target of Muromonab-CD3 (OKT3)?

CD3 (p.210)

10

What is the therapeutic target of Digoxin Immune Fab?

Digoxin (p.210)

11

What is the therapeutic target of Infliximab?

TNF-a (p.210)

12

What is the therapeutic target of Adalimumab?

TNF-a (p.210)

13

What is the therapeutic target of Abciximab?

Glycoprotein Iib/IIIa (p.210)

14

What is the therapeutic target of Trastuzumab?

HER2 (p.210)

15

What is the therapeutic target of Rituximab?

CD20 (p.210)

16

What is the therapeutic target of Omalizumab?

IgE (p.210)

17

What is the clinical use of Muromonab-CD3 (OKT3)?

To prevent acute transplant rejection (p.210)

18

What is the clinical use of Digoxin Immune Fab?

Antidote for digoxin intoxication (p.210)

19

What is the clinical use of Infliximab?

Crohn's disease, Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (p.210)

20

What is the clinical use of Adalimumab?

Crohn's disease, Rheumatoid arthritis, psoriatic arthritis (p.210)

21

What is the clinical use of Abciximab?

To prevent cardiac ischemia in unstable angina and in patients treated with percutaneous coronary intervention (p.210)

22

What is the clinical use of Trastuzumab?

HER2 overexpressing breast cancer (p.210)

23

What is the clinical use of Rituximab?

B cell non Hodgkin's lymphoma (p.210)

24

What is the clinical use of Omalizumab?

Additional line of treatment for severe asthma (p.210)