Infección intrauterina de CMV (28) Flashcards

1
Q

Clinica

A
  • Microcefalia
  • Ictericia
  • Purpura
  • Hepatoesplenomegalia
  • Pérdida auditiva
  • Coriorretinitis
  • Deficit neurologico primeros 2 años
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2
Q

Trasmisión in utero

A

A mayor edad gestacional, mayor riesgo de trasmisión
- Gravedad es mayor en 2T y 3T
- Mayor trasmisión en 3T

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3
Q

Presentación más frecuente in utero

A

Asintomática (90%)

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4
Q

Hallazgo más frecuente

A

RM anormal
- TAC craneal anormal
- USG craneal anormal
- Transaminasemia
- Trombocitopenia
- Hepatoesplenomegalia

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5
Q

FR mas importante en infección materna

A

Exposición frecuente y prolongada a niños pequeños (excretan virus por orina y saliva por 24 meses)

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6
Q

Clinica en embarazada

A
  • Asintomatica
  • Fiebre
  • Cuadro gripal o mononucleosido
  • Linfocitosis
  • Trombocitopenia
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7
Q

Metodo dx en RN

A

Cultivo viral: de tejidos obtenidos de biopsia o de muestras de orina o saliva tomadas los primeros 15 días de vida.

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8
Q

Tx

A

Ganciclovir (neutropenia) o valganciclovir

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9
Q

Secuela más frecuente

A

Hipoacusia y sordera sensorial (primera causa en niños)
- Paralisis cerebral
- Trastornos cognitivos

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10
Q
A
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11
Q
A
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