Infections in Immunocomp Host pt 2 Flashcards Preview

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Flashcards in Infections in Immunocomp Host pt 2 Deck (23):
1

If you have neutropenia less than 7 days what bacteria could you suspect?

Staph, Strep, Pseudomonas, E. coli and Klebsiella

2

If you have neutropenia greater than 10 days what fungi might accompany the bacteria?

Aspergillus and Candida sp.

3

What can cause neutrophil count to fall?

Cancer medications

4

What could be used to prevent opportunistic fungi?

Candida or aspergillus

5

What are some broad spectrum IV antibiotics?

Ceftazidime, cefepime
Carbapenem if beta-lactamase needed

6

What drug would be used for prevention of opportunistic fungi?

Caspofungin

7

What could Sabourauds agar be used to indentify?

Candida

8

What diseases does Candida cause?

Thrush
Vagina yeast infections
Esophagitis
Candidemia
Hepatospenic candidasis

9

What is the treatment for Candida?

Echiocandins (caspofungin)
Fluconazole
Voriconazole
Amphotericin B

10

What are some causes of neurological symptoms in AIDS patients?

CNS lymphoma
AIDS dementia complex
Cryptococcal meningitis
Toxoplasma gondii encephalitis
Progressive multifactorial leukoencephalitis
CMV encephalitis

11

What are ring-enhancing lesions in the brain associated with?

Lymphoma
Toxoplasmosis
Cryptococcosis

12

How is Toxoplasma gondii treated?

Pyrimethamine (inhibitor of folate synth)
Sulfadiazine (inhibitor of folate synth)
Leukovorin (folinic acids to overcome bone marrow suppressive effects of folic acid antagonists
If intolerant of sulfa drugs Clindamycin + pyrimethamine

13

How do you prevent Toxoplasma gondii in AIDS patients?

TMP/SMX (CD4 count below 200)

14

In healthy people what does Toxoplasma gondii cause?

Mono like symptoms

15

If an infant is born while the mother is infected what could it lead to?

Hydrocephalus, microephaly, intercranial calcification
Classic triad - chorioretinitis, hydrocephalus, calcification

16

What are the long term manifestations of congenital toxoplasmosis?

Deafness
Visual impairment
Learning disabilities

17

What organism will cause profuse, non-bloody, watery diarrhea with nausea, vomiting and lower ab cramping?

Cryptosporidium

18

What are the characteristics of Crypto hominis?

Sporozoite that follows the ingestion of contaminated food or water (like pools)

19

Where does the parasite of Cryptosporidium replicated in the host?

Ingested as oocyst
Replicates under brush border of intestine
Male and female gametes formed
Zygote to oocyst shed in feces

20

What is the treatment for Crytospotidiosis?

Nitazoxanide in normal infection

21

Where will you find the larvae of Strongyloides stercoralis?

CNS, heart, urinary tract, endocrine glands

22

What organism is associated with corticosteroid treatments?

Strongylodies stercoralis

23

How would you treat Strongylodies stercoralis?

Thiabendazole