Infectious Flashcards
(46 cards)
Which leptospirosis interrogans serovars are the most common in North America?
Canicola and icterohemorrhagia
The snap ELISA for leptospirosis detects what?
Antibodies (IgG > IgM) against LipL32
*** Not as good as Witness for acute infection
Pneumonyssus, euvolemia and cuterebra can all infect which system?
Nose
Which bacteria can be transmitted through raw food?
Campylobacter Enterococcus E.coli Staphylococcus aureus Salmonella
Which parasites can be transmitted through raw food?
Cryptosporidium Echinococcus Giardia Neospora Toxocara Toxoplasma
Which immunoglobulin is usually produced first ?
IgM
Which immunoglobulin usually remain high for very long time?
IgG
Which breed are predisposed to membranoproliferative Lyme nephritis?
Golden and Labrador
Leptospirosis canicola, Bratislava and gryppotyphosa mostly affect which system?
Renal +hepatic
Leptospirosis icterohemorrhagia and Pomona mostly affect which system?
Hepatic
What are the 3 forms of transmission from Yersinia pestis?
Flea - rodent that can be ingested, scratch or inhaled
What are the clinical signs of Yersinia pestis? Name a diagnostic method? Treatment?
Lymph nodes abscess
DIC
Fever
Rare in dogs
Culture of tonsils
Gentamicin
What is the diagnostic method of franciscella tularensis?
Gram -
Microscopy agglutination of antibodies
Treatment with gentamicin and surgery
What is the diagnostic method of franciscella tularensis?
Gram -
Microscopy agglutination of antibodies
Treatment with gentamicin and surgery
What are the signs of coxiella Burnett I? Diagnosis ?
Treatment?
Atypical pneumonia, vascular is, splenomegaly, fever, abortion
IgG titers
Tetracycline and chloramphenicol
What is the treatment for mycobacterium?
Rifampin
Clarithomycin
Isoniazid
Which are the states where blastomycosis and histoplasmosis are frequent?
Ohio
Missouri
Mississippiq
For lyme disease, what is the gram, mode of transmission and diagnosis?
Gram -
Tranmission - Ixodes transmit OpsA
Snap 4dx - C6 Western Blot OpsA - indicates vaccination OpsC - antibodies within 2-3 weeks, then wean after 5 months OpsF - persists
For babesia, indicates the transmission, main system affected and treatment.
Gibsoni
Canis vogeli
Canis
Gibsoni - pitbull
Canis vogeli - rhipicephalus
Canis - dermacentor
Main system: IMHA, DIC
Treatment:
Gibsoni: Atovaquone + azithromycin
Canis: imidocarb
For bartonella, indicate the gram, which specific cells it invades, the 2 main diagnostics methods and specific treatment recommendations.
Gram - facultative IC
Feces from flea invade endothelial cells CD34+
Diagnosis: DNA of affected tissues, Enrichement PCR
Treatment: second antibiotic needs to be started 5-7 days after the first t o avoid Jarisch-Herxheimer
1) Doxycycline + baytril
2) Azythromycin + rifampin
For hepatozoon americanum, describe the 3 phases and their associated clinical signs, 2 methods of diagnosis and treatment.
Phases: 1) Sporozoite within GI 2) Merozoites: pyogranuloma 3) Gamonts - infectious organism Fever, painful gait from periosteal proliferation, mucopurulent ocular discharge, glomerulo-nephritis
Diagnosis:
Biopsies of femoris or semitendinous
PCR
Treatment:
Clindamycin + pyrimethamine
Decoquinate to decrease recurrence
For neospora, what are the 2 methods of transmission, clinical signs, diagnosis and treatment
Transmission
- Bradyzoites in meat (horizontal)
- Tachyzoites in placenta (vertical)
Clinical signs:
- Young: ascending paralysis and HL rigidity, megaesophagus
- Older: can have myocarditis and CNS
Diagnosis:
Antibody (IF)
Biopsies (Light microscopy)
Treatment: none
TMS, pyrimethamine +/- clindamycin
For leptospirosis, which gram ? Which is the best diagnostics methods?
Gram -
Diagnosis via micro-agglutination (IgM and IgG) or PCR if within 10 days of infection
For Ehrlichia, which tick for:
Canis
Chaffensis
Ewingii
Clinical signs, more severe in which breed, the chronic forms lead to which issue.
Diagnosis
Coinfection
Canis - Rhipicephalus
Chaffensis - Amblyomma or dermacentor
Ewingii - Amblyomma phagocytophilium
Clinical signs: Ewingii = IMPA, polymyositis, CNS, uveitis.
More severe in German Shepherd
The chronic forms lead to bone marrow hypoplasia
Diagnosis:
Serology 8-20 days after inoculation
PCR within 10 days
Coinfection with Anaplasma platys, babesia, hepatozoon and rickettsia