Inflammation - Powerpoint Flashcards
(16 cards)
What is the origin of the word ‘inflammation’?
It comes from the Latin ‘inflammare’, meaning to ‘ignite’ or ‘set fire to’.
This reflects the intense response associated with inflammation.
What does inflammation refer to?
The process of response to foreign invasion or injury to the tissues.
This response is crucial for the body’s defense mechanisms.
What is the purpose of inflammation?
To remove the insult and repair any damage.
Inflammation is a vital part of the healing process.
What are mast cells?
Granule filled cells located in the loose connective tissues close to blood vessels
Mast cells play a crucial role in the immune response.
Where are mast cells typically found?
In the loose connective tissues close to blood vessels
Their location allows them to respond quickly to pathogens.
What type of tissues do mast cells associate with?
Loose connective tissues
This association supports their function in immune surveillance.
Mast cells are often described as _______.
First responders
They are among the first immune cells to react to infections.
What are neutrophils also known as?
Polymorphonuclear neutrophils (PMNs)
Neutrophils are the first immune cells to arrive at the site of infection.
What role do neutrophils play in the immune response?
Professional killers, often referred to as ‘Kamikaze cells’
Neutrophils sacrifice themselves to eliminate pathogens.
What do monocytes develop into in tissue?
Macrophages
Monocytes arrive at the infection site approximately 24 hours after neutrophils.
How long after neutrophils do monocytes arrive at the infection site?
Approximately 24 hours
This timing is crucial for the transition from acute to chronic inflammation.
What is the primary function of eosinophils?
Defense against parasites and regulation of vascular mediators
Eosinophils have a mildly phagocytic capacity.
What types of cells do natural killer (NK) cells recognize and eliminate?
Virus-infected cells and possibly cancer cells
NK cells play a critical role in the innate immune response.
What is a hormone?
A hormone is the primary product of a specific tissue or cell.
Hormones are typically involved in regulating physiological processes in the body.
What is a cytokine?
Cytokines are considered the ‘hormones’ of immune and inflammatory responses.
Cytokines can be produced by most cells in the body and have various roles in cell signaling.
How do cytokines differ from hormones?
Cytokines are products of most cells, while hormones are the primary products of specific tissues or cells.
This distinction highlights the broader range of sources and functions of cytokines compared to hormones.