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Flashcards in Interstitial Lung Disease Deck (18)
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1

What is interstital lung disease?

Wide spread lung fibrosis

2

What can cause ILD?

Occupational
- fumes
- asbestos
Sarcoidosis
SLE
Amyloidosis

3

What happens in fibrosis?

Replacement of damaged cells
- injured with inflammation

Focal fibrosis = response to irritants

Diffuse parenchymal diseae
- occurs with idiopathic lung disease
- extrinsic allergic alveolitis

4

What can cause upper-middle zone ILD?

Aspergillosis
Pneumoconiosis
Extrinisic allergic alveolitis
Negative sero arthropathies
TB

5

What can cause mid-lower zone?

Sarcoidosis
Toxins
Asbestosis
Idiopathic pulmonary fibrosis
Rheum

6

What is idiopathic pulmonary fibrosis?

Lungs enter pro-inflammatory state driven by macrophages and fibroblasts

Promotes fibrosis and destruction of alveoli

7

What is the spirometry patter of idiopathic pulmonary fibrosis?

Restrictive

8

What is the presentation of ILD?

SoB
Dry cough
Inspiratory fine crackles
Clubbing

9

What is the spirometry pattern of ILD?

Restrictive pattern

Reduced FVC
Normal FEV-1

10

What investigations would you do for ILD?

Bloods
- FBC
- U+Es
- CRP

CXR

HR-CT

11

What would the CXR show?

Reduced lung volume
Increased lung markings

12

What would the HRCT show?

Honeycomb sign
- large airspaces with fibrotic walls

13

How is ILD managed?

Pulmonary rehab
Smoking cessation

Acute exacerbation = corticosteroids

14

What is extrinsic allergic alveolitis?

Hypersensitivity reaction caused by inhalation of allergens

15

What can cause EAA?

Bird fancier's lung
Farmer's lung
Malt worker's lung

16

What are the acute clinical features of EAA?

Fever
Rigors
Myalgia
Dry cough
Dyspnoea

17

What are the chronic clinical features of EAA?

Increasing dyspnoea
Weight loss
Type 1 respiratory failure

18

How is EAA managed?

Allergen avoidance
Steroids