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Flashcards in TB Deck (25)
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1

What are the common causative organisms?

Mycobacterium tuberculosis
Mycobacterium bovii
Mycobacterium africanum

2

What is primary TB?

Spread by droplets and engulfed by macropahges

3

Where does primary TB tend to effect?

Hilum

4

What is secondary TB?

Reactivation of TB due to immune impairment

5

Where does secondary TB tend to effect?

Apices

6

What is miliary TB?

Occurs when primary infection is not contained and spreads to bloodstream

7

What are risk factors for TB?

Contact with TB
Foreign travel
Immunosuppressed
IV drug users
Homeless

8

What are the symptoms of respiratory TB?

B symptoms
Cough
SOB
Haemopytsis
Malaise

9

What are symptoms of non-respiratory TB?

Erythema nodosum
Meningitis symtpms
Lymphadenopathy
Bone pain

10

How do you investigate suspected TB?

Sputum culture - acid fast bacilli

Bloods
- quantiferon gold
- blood borne virus screen

CXR
CT chest

11

What stain do you use for TB?

Ziehl-Neelsen

12

What medium is TB sputum cultured on?

Lowenstein-Jensen slope

13

What are the CXR findings in TB?

Consolidation
Cavitating lesion

14

What is the treatment for pulmonary TB?

Rifampicin 6/12
Isoniazid 6/12
Pyrazinamide 2/12
Ethambutol 2/12

15

What is the treatment for TB meningitis?

Rifampicin 12/12
Isoniazid 12/12
Pyrazinamide 2/12
Ethambutol 2/12

16

What are the side effects of rifampicin?

Hepatitis
Orange secretions

17

What are the side effects of isoniazid?

Hepatitis
Peripheral neuropathy
Rashes

18

What are the side effects of ethambutol?

Optic neuritis

19

What are the side effects of Pyrazinamide?

Hepatitis
Arthralgia
Rashes

20

What is MDR TB?

Multi drug resistant TB
- resistant to more than one drug

21

What is XDR TB?

Extensively drug resistant TB
- resistant to more than 3 drugs

22

Is TB a notifiable disease?

Yes

23

What TB prophylaxis is available?

BCG

Isoniazid

24

When is prophylaxis indicated?

HIV
Recent exposure to TB
No BCG + mantoux >5mm
BCG + mantoux >10mm

25

What is the mantoux test?

Injection of dilutions of TB antigen under skin

>10mm = postive
<5mm = negative