Flashcards in Interstitial Lung Disease, The Pleura And Chest Wall Deck (37)
What is the interstitium of the lungs?
Space in between alveoli and bloodstream
Needed to function
What is the role of the lung interstitium?
Conduit for things to leave circulation and vice versa
Interstitial diseases can affect many different parts of anatomy/physiology, name a few
Interstitial lung disease is what type of defect
What would the FEV1/FVC ratio for ILDs look like
Therefore ratio about normal
What is a common CXR finding for ILD?
Looks like lace over the lungs
What do we call the rounded cystic areas in ILD?
What are the 2 main symptoms of any ILD?
Chronic shortness of breath
Give some signs on examination that would chest ILD
Signs of RH failure
Decreased chest movement
What are the classifications of ILDs?
Connective tissue disease
What is the largest group of ILDs?
Name some causes of occupational ILD
Coal dust (coal workers pneumoconiosis)
Name some treatments that can cause ILD
Nitrofurantoin (given for UTI)
Name some connective tissue diseases that can lead to ILD
Name some immunological problems that can cause ILD
Describe idiopathic pulmonary fibrosis (IPF)
Median survival = 3 years
Often diagnosed via CT
There are new therapies to treat: antifibrotics and vegF inhibitors
Interstitial lung disease caused by asbestos
Other than asbestosis, what other problems can asbestos exposure lead to?
Diffuse pleural thickening
Benign asbestos pleural effusions
Bronchogenic lung cancer
Sometimes a cough and rash
Lung function tests can be normal or abnormal
Differential: lymphoma and TB
What is the treatment for sarcoidosis?
Sometimes no treatment
Which pleura has somatic innervation?
Only the parietal
Describe pleuritic pain
Worse with inspiration
What is the rate of pleural fluid turnover?
How can liver cirrhosis affect the pleura?
Lack of production of albumin
Decreased oncotic pressure
Increased production of pleural fluid
What changes would cause increased production of pleural fluid?
Increased hydrostatic pressure capillaries
Decreased oncotic pressure capillaries
What would cause decreased absorption of the pleural fluid?
Elevated systemic venous pressure
To be called an exudate, pleural protein divided by serum protein must be ...
(And LDH > 0.6)
What might we analyse pleura fluid for?
What is pleural empyema?
Pockets of fluid
Not evenly affecting the lung