Introduction Flashcards

(45 cards)

1
Q

what si he need fro an immune system

A

protection against microorganisms

protection from cancer

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2
Q

what are some infectious organisms

A
bacteria - mycobac, s.cocci
viruses- polio, HIV
Fungi- candida
protozoans- malaria 
worms- tapeworms
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3
Q

what is a way of describing the immune system

A

multi lead protected from variety of diseases

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4
Q

what is the immune systems overlapping capacity

A

if org invades one part the other pars kick in

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5
Q

how many diff viruses, bac, protozoans, worms are there

A

viruses - 208
bac - 538
protozoans - 57
worms - 287

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6
Q

what are the two major systems of immunity

A

innate and adaptive

work together and cooperate

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7
Q

what are the physical barriers of inane immunity

A

imperm outer surface - skin, epi

cilia in nasla passie and bronchi

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8
Q

what are the chemical barriers of innate immune cyst

A

acidity of stomach
alkaline secretions
lysosome in tears

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9
Q

what are some biological barriers of the innate cyst

A

comp with commensal organisms

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10
Q

what does commensal mean

A

harmless

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11
Q

what are the mechanics of the innate immune system in GI tract

A

most pathogens destroyed by low pH of stomach

few pathogens reach bowel compete with millions gut bacteria

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12
Q

what is innate immunity

A

first line of defence

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13
Q

when is innate immunity present

A

from birth

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14
Q

how does innate syst respond

A

rapidly

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15
Q

does the innate immune syst have specificity or memory

A

no and no

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16
Q

what can the innate immune system be described as

A

barriers, soluble factors, cells

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17
Q

what are some innate system barriers

A

low pH and commensals in vagina
flush urinary tract and acidity of urine
bronchi mucus and cilia

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18
Q

what are some cells involved in innate immunity

A

phagocytes
NK cells
eosinophils

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19
Q

what are some phagocytes

A

monocytes
macrophages
neutrophils

20
Q

what are NK cells

A

kill tumour cells and virally infected cells

21
Q

what are eosinophils

A

attack and kill parasites

22
Q

what re the soluble factors of the innate immunity

A

lysosome
complement
cytokines particularly interferons
acute phase proteins

23
Q

what si the cooperation of innate immunity

A

components of innate system act together

also coop with adaptive immunity

24
Q

what is complement

A

complicated system

efficient way kill pathogens

25
what are cytokines
varied group molecules | capable of signalling between immune cells, trigger loads diff effects, inflam reaction
26
what is an interferon
type of cytokine
27
what are acute phase proteins
used conc go up when have infection markers of infection but there to help coord a response
28
what is adaptive immune system
slow to start - lag phase | adaptive - tailored response
29
is the adaptive system specific or have memory
highly sp and has memory recon self and non-self
30
what are the components that work in concert with each other for adaptive system
humoral an cellular
31
what is humoral immunity
antibodies - IgA | sp protiens prod by immune system used ag pathogens
32
what produces antibodies
B lymphocytes
33
what is the cellular immunity of the adaptive immunity mediated by
lymphocytes which reg sp antigens
34
what are the types of lymphocytes
B | T
35
what are the types of T lymphocytes
helper T cells - prod antibodies cytotoxic- destroy own cells which have been infected with virus
36
what si the difference between 1st (primary) response and 2nd
primary - slow vaccination mock disease secondary - rapid, alor more antibody prod
37
what are the pioneers of vaccination
edward jenner | pasteur
38
what is smallpox
acute contagious disease caused by variola virus
39
what s the effect of vaccination
vast decrease of cases
40
what are the to main roles of immune system
recognition - identify substance/body as foreign effector function-removes foreign invader
41
what is an antigen
any substance which elicits an immune response
42
what si the portion recognised by antigen determinants
epitope or antigenic determinant
43
what are microorganisms made up of
many macromolecules, each may be antigenic. each macromolecule will contain many antigenic determinants
44
what recognise antigen determinant
antibodies - humoral | T cells - cellular
45
what are some types f antigen
``` proteins carbs nucleic acids lips drugs inorganic molecules ```