introduction to viruses

Question 1

characterized by a rapid onset of flaccid weakness in one or more limbs and distinct abnormalities in spinal cord grey matter on magnetic resonance imaging

Answer 1

acute flaccid myelitis

Question 2

AFM is related to

Answer 2

Polio

Question 3

viral genes do not need to encode the same signals as those from the human gene

Answer 3

false, same signals needed

Question 4

the physical particle, infectious or transmissible, but cannot replicate

Answer 4

virion

Question 5

the viral genome, structural proteins, and enzymes necessary to generate new virions inside the host cell

Answer 5

replicative form

Question 6

virions have three essential components

Answer 6

1. capsid
2. ribonucleoprotein
3. enzymes

Question 7

ordered array of proteins that provides the structural integrity

Answer 7

capsid

Question 8

aids on folding/ condensation of the genome (often a chaperone)

Answer 8

protein from ribonucleoprotein

Question 9

often includes a polymerase, integrase

Answer 9

enzymes

Question 10

membrane derived from host cell

Answer 10

envelope

Question 11

glycosylated (often heavily) protein embedded in the envelope

Answer 11

envelope glycoprotein

Question 12

protein lattice

Answer 12

capsid HPV

Question 13

viruses can exhibit two distinct symmetries

Answer 13

1. cylindrical

2. icosahedral

Question 14

virions can incorporate any amount of volume and potentially variable amount of genetic material by varying the length of the cylinder

Answer 14

cyclindrical

Question 15

ebola symmetry

Answer 15

cylindrical

Question 16

virions incorporate a fixed dvolume, and a fixed amount of genetic material and are highly homogenous

Answer 16

icosahedral

Question 17

linear, double stranded

Answer 17

DNA

Question 18

linear, single stranded

Answer 18

DNA

Question 19

circular, single stranded

Answer 19

DNA

Question 20

linear, plus stranded

Answer 20

RNA

Question 21

linear minus stranded

Answer 21

RNA

Question 22

segmented, minus stranded

Answer 22

RNA

Question 23

segmented, double stranded

Answer 23

RNA

Question 24

differential splicing occurs in

Answer 24

HIV

Question 25

interaction between virus protein and cell surface receptor

Answer 25

attachment

Question 26

receptor-mediated endocytosis or direct interaction at the cell surface leading to fusion of virus and cell membranes

Answer 26

penetration

Question 27

release of nucleic acid (+/- enzymes) for expression

Answer 27

uncoating

Question 28

depend on virus group and prepare for nucleic acid replication

Answer 28

early events in transport to site replication

Question 29

nucleic acid replication, virion protein sythesis and virion assembly and release.

Answer 29

late events in transport to site replication