Investigating the endocrine system Flashcards Preview

Clinical Pathology > Investigating the endocrine system > Flashcards

Flashcards in Investigating the endocrine system Deck (13):
1

How do hormones work?

Chemicals secreted by endocrine glands, circulate and influence other tissues, only influence cells that have specific target receptors

2

Pituitary gland

Regulates cortisol (ACTH, GH), reproductive function (FSH, LH) and TSH

3

Feedback regulation

Hypothalamus > anterior pituitary > endocrine organ

4

FSH stimulate

Sertoli cells, seminiferous tubules, maturation of sperm (inhibin)

5

LH stimulates

Leydig cells (testosterone)

6

Low TSH, low thyroxine

Pituitary failure

7

High TSH, low thyroxine

Unresponsive thyroid

8

Low TSH, high thyroxine

Thyroid gland overproduction

9

Low TSH, high thyroxine

Pituitary gland overproduction/feedback fails

10

Cortisol

Produced by adrenocortex (outside of adrenal gland)

11

Cushing's

Obesity (moon face, central, shoulders), thin skin, purple striae, bruising, hypertension, glucose intolerance, menstrual disturbances/impotence, thin limbs, muscle weakness, back pain (osteoporosis), psychiatric disturbances (depression, psychoses)

12

Adrenal failure (ACTH)

(Adrenal atrophy/destruction) Tiredness, weight loss, pigmentation, hypoglycaemia, abdominal pain, hypovolaemic collapse

13

What to take a blood sample?

- Hormones change daily/monthly
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