Irritable Bowel Syndrome Flashcards Preview

JL Gastrointestinal > Irritable Bowel Syndrome > Flashcards

Flashcards in Irritable Bowel Syndrome Deck (12):
1

What is the peak age group for IBS?

30-40

2

What is visceral hypersensitivity related to?

IBS

3

What are the two mechanisms in visceral hypersensitivity?

Peripheral sensitisation
Central sensitisation

4

What visceral hypersensitivity mechanism involves increased sensitivity of spinal neurones?

Central sensitisation

5

What visceral hypersensitivity involves inflammatory mediators up-regulating sensitvity of nociceptor terminals?

Peripheral sensitisation

6

What are two changes to diet that can be made to help IVS?

Regular meal times, reduce fibre

7

With IBS what drugs should be stopped?

Opiate analgesia

8

What three classes of drugs could be given to help IBS?

1. Anti-diarrhoeals
2. Anti-spasmodics
3. Anti-depressants

9

What can prolonged use of opiates lead to?

Opiate/narcotic bowel syndrome

10

Name two anti-spasmodics?

Mebeverine
Hyoscine

11

Name an anti-diarrhoeal?

Loperamide

12

Name a tricyclic used as an anti-depressant?

Amitriptyline