Dyspepsia and Peptic Ulcer Disease Flashcards
(19 cards)
What are epigastric pain or burning (epigastric pain syndrome), post-prandial fullness (postprandial distress syndrome) and early satiety (postprandial distress syndrome)?
Dyspepsia
What are 5 foregut structures?
Oesophagus, stomach, duodenum, pancreas and gallbladder
oh such difficult positioning games
What are organic causes of dyspepsia?
Peptic ulcer disease
Drugs (NSAIDs, COX2 inhibitors)
Gastric cancer
If dyspepsia presentation has alarm symptoms, what should you check for?
H.pylori
What criteria are these: presence of one of the following - bothersome postprandial fullness, early satiation, epigastric pain and epigastric burning?
Rome III diagnostic criteria for functional dyspepsia
What is the pain like in peptic ulcer disease?
Pain predominant dyspepsia to back, nocturnal, aggravated or relieved by eating
What are the two most common causes of peptic ulcer diease?
H. pylori
NSAIDS (COX1, COX2 and PGE)
What is a gram negative microaerophilic flagellated bacillus?
H.pylori
How is H.pylori transmitted?
Oral-Oral/faecal oral spread
When is H.pylori aquired?
In infancy
What is found in 95% of duodenal ulcers and 75% of gastric ulcers?
H. pylori
What do parietal cells produce?
Hydrochloric acid
What are 4 methods for diagnosing H.pylori?
Gastric biopsy
C13UREA BREATH TEST
FAT (faecal antigen test)
Serology (IgA antibodies)
What enzyme is present in the stomach if H.pylori is present?
Urease
What drug should be given to all PUD patients and what test performed?
PPI
Urea breath test
What drugs should be withdrawn in PUD?
NSAIDs
What is the triple therapy for eradicating H.pylori?
- PP1 + amoxicillin + clarithromycin
2. PPI + metronidazole + clarithromycin
What are anaemia, bleeding, perforation and gastric outlet/duodenal obstruction complications of?
PUD
How should GU patients be followed up?
Endoscopy at 6-8 weeks
