IX - General Pathology of Infectious Diseases Flashcards Preview

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Flashcards in IX - General Pathology of Infectious Diseases Deck (24)
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1
Q
These agents cause transmissible spongiform encephalopathies.
A
Prions(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 321
2
Q
Infected cells show distinct nuclear and ill-defined cytoplasmic inclusions.
A
CMV infection(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 322
3
Q
Infected cells show glassy nuclear inclusions, frequently with a surrounding halo.
A
Herpesvirus infection(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 322
4
Q
Infected hepatocytes show diffuse granular (ground-glass) cytoplasm.
A
Hepatitis B viral infection(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 322
5
Q
Sexually transmitted protozoan that can colonize the vagina and male urethra.
A
Trichimonas vaginalis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 325
6
Q
Protozoan acquired either by contact with oocyte-shedding kittens or by consumption of cyst-ridden undercooked meat.
A
Toxoplasma gondii(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 325
7
Q
Size of microorganisms for them to be inhaled directly into the alveoli.
A
5 um(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 327
8
Q
These microorganisms grow in contaminated food and releases powerful enterotoxins that cause food poisoning symptoms without any bacterial multiplication in the gut.
A
Staphylococcal strains(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 327
9
Q
Intestinal helminth that cause disease when present in large numbers or cause obstruction of the gut.
A
Ascaris lumbricoides(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 326
10
Q
Helminth that causes iron deficiency anemia by chronic loss of blood.
A
Hookworms(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 327
11
Q
Helminth that depletes vitamin B12 giving rise to an illness resembling pernicious anemia.
A
Diphyllobotrium latum(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 327
12
Q
Placentofetal route as a mode of transmission is also referred to as ________.
A
Vertical transmission(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 329
13
Q
The ability of bacteria to cause disease.
A
Virulence(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 331
14
Q
Bacterial surface molecules that bind to host cells.
A
Adhesins(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 332
15
Q
Filamentous proteins on gram negative bacteria which allow exchange of genes between bacteria, and also involved in adherence.
A
Fimbriae/pili(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 332
16
Q
Clostridium perfringens produces this toxin that disrupts plasma membranes resulting in digestion of host tissues and collagen.
A
Alpha toxin (lecithinase)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 334
17
Q
Bacterial toxins with the capacity to stimulate large populations of T lymphocytes, functionally resulting in a "cytokine storm".
A
Superantigens(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 334
18
Q
Examples of antigen presenting cells.
A
Dendritic cellsMacrophagesB-cells(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 334
19
Q
A superantigen secreted by S. aureus which causes inflammation, fever and shock. Found in the vagina of menstruating women.
A
Toxic shock syndrome toxin (TSST-1)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 334
20
Q
Collection of neutrophils which gives rise to localized liquefactive necrosis.
A
Abscess(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 334
21
Q
High risk agents of bioterrorism which are easily disseminated and has high potential for mortality. An example is smallpox.
A
Category A(TOPNOTCH)
22
Q
A distinctive form of mononuclear inflammation usually evoked by infectious agents that resist eradication, but are capable of stimulating strong T cell mediated immunity. Characterized by epitheloid cells which may fuse to form giant cells.
A
Granulomatous inflammation(TOPNOTCH)Robbins Basic Pathology, 8th Ed p. 335
23
Q
Agents that are relatively easy to disseminate and produces moderate morbidity and low mortality. An example is E.coli O157:H7 which can cause HUS.
A
Category B(TOPNOTCH)
24
Q
Includes emerging pathogens that have the potential for mass dissemination with high morbidity and mortality. Examples are Nipah virus and Hanta virus.
A
Category C(TOPNOTCH)

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