V - Diseases of the Immune System Flashcards Preview

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Flashcards in V - Diseases of the Immune System Deck (116)
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1

Type of immunity mediated by neutrophils, macrophages and natural killer cells and includes epithelial barriers of the skin, GIT and respiratory tract.

Innate immunity (natural/native)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.108

2

Type of immunity mediated by lymphocytes and their products, and is normally silent and responds to the presence of microbes by becoming active, expanding and generating potent mechanisms for neutralizing and eliminating microbes.

Adaptive immunity (acquired/specific)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.108

3

Type of adaptive immunity mediated by soluble antibody proteins that are produced by B lymphocytes. Effective against extracellular microbes.

Humoral immunity(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.109

4

Type of adaptive immunity mediated by T lymphocytes. Designed to combat cell-associated microbes (e.g. Phagocytosed microbes and microbes in the cytoplasm of infected cells).

Cell-mediated or cellular immunity(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.109

5

Results from activation of TH2 CD4+ helper T cells by environmental antigens, leading to the production of IgE antibodies, which become attached to mast cells.

Type I Hypersensitivity (immediate)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120 *SEE SLIDE 5.1

6

Caused by antibodies that bind to FIXED TISSUE AND CELL ANTIGENS and promote phagocytosis and destruction of the coated cells or trigger pathologic inflammation in tissues.

Type II Hypersensitivity (Antibody-mediated)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120 *SEE SLIDE 5.1

7

Caused by antibodies binding to antigens to form COMPLEXES that circulate and may deposit in vascular beds and stimulate inflammation, secondary to complement activation.

Type III Hypersensitivity (immune complex mediated)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120 *SEE SLIDE 5.1

8

Cell-mediated immune responses in which T lymphocytes cause tissue injury, either by producing cytokines that induce inflammation and activate macrophages, or by directly killing cells.

Type IV Hypersensitivity (T-cell mediated/Delayed)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120 *SEE SLIDE 5.1

9

Indicate type of hypersensitivity reaction:SLE

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

10

Indicate type of hypersensitivity reaction:Multiple sclerosis

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

11

Indicate type of hypersensitivity reaction:Transplant rejection

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

12

Indicate type of hypersensitivity reaction:Anaphylaxis

Type I(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

13

Indicate type of hypersensitivity reaction:Goodpasture syndrome

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

14

Indicate type of hypersensitivity reaction:Serum sickness

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

15

Indicate type of hypersensitivity reaction:Arthus reaction

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

16

Indicate type of hypersensitivity reaction:Autoimmune hemolytic anemia

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

17

Indicate type of hypersensitivity reaction:Allergies

Type I(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

18

Indicate type of hypersensitivity reaction:Type I DM

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

19

Indicate type of hypersensitivity reaction:Tuberculosis

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

20

Indicate type of hypersensitivity reaction:Bronchial asthma

Type I(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

21

Indicate type of hypersensitivity reaction:Acute rheumatic fever

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

22

Indicate type of hypersensitivity reaction:Poststreptococcal glumerulonephritis

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

23

Indicate type of hypersensitivity reaction:Polyarteritis nodosa

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

24

Indicate type of hypersensitivity reaction:Rheumatoid arthritis

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

25

Indicate type of hypersensitivity reaction:Inflammatory bowel disease

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

26

Indicate type of hypersensitivity reaction:Tuberculin reaction

Type IV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

27

Indicate type of hypersensitivity reaction:Reactive arthritis

Type III(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

28

Indicate type of hypersensitivity reaction:Graves disease

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

29

Indicate type of hypersensitivity reaction:Acute rheumatic fever

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

30

Indicate type of hypersensitivity reaction:Myasthenia gravis

Type II(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.120

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