Atenolol
?
Dobutamine
Selective B1 agonist (can activate both B1 and B2)
Heart failure and cardio genie shock
Epinephrine
A & B DNS
Isoproterenol Type Effects Side effects Admin Absorption Excretion
Non selective B Agonist (low affinity A)
Cardio: Decreased peripheral resistance (skeletal m, renal and mesenteric beds)
decrease MAP
Increased cardiac output via HR and contractility (iono& chronotropic)
Smooth muscle: relax esp bronchial and GI
Sinus tachycardia /palpitations/arrhythmias/myocardial necrosis
Parenterally/ aerosol
Metab via liver
Longer 1/2 life than NE and EP but still short
Norepinephrine
A
DNS
Phenylephrine
Selective/non selective?
Effects?
Uses?
Side effects
Half life
Metabolism
Selective A1 (adrenergic receptor) agonist
Agonist
Nasal decongestant & increase BP
Used for hypotension as vasopressor (sepsis)
Increases BP w/ no change in HR or contractility
Reflex bradycardia possible
Short half-life
Prazosin
A1 selective blocked
Propranolol
NS B blocker B
Phentolamin
NS A blocker
Terbutaline
DS
B2
Xylazine
Selective
Yohimbine
A2 blocker
