Kidney Flashcards
(16 cards)
Which gene controls the function of Podocytes
WT-1 suppressor gene
Acute nephritic syndrome symptoms
Haematuria Oliguria Edema Proteinuria HTN
Proteinuria in Nephritic syndrome values
0.5-3 g/day
Which case will give us linear immunufluorescence
Anti glomerular basement membrane Ab
Glomerulopathies associated with Nephrotic syndrome
Minimal change disease
FSGS
Membranous nephropathy
MCD main symptom
Highly selective proteinuria- Albuminuria
MCD response to corticosteroids
Good
What will we see on EM in MCD
Disappeared slit membrane of the podocytes
EM of FSGS will show us
Effacement of foot process
Detachment of foot process
FSGS
Focal Segmental Glomerulo-Sclerosis
Location of “tip” lesion in FSGS
Proximal tubule
Tip lesion response to steroids
Good
Most common type of FSGS
Perihilar type
Membranous nephropathy IF will show us
IgG
Membranous nephropathy- where does the immunocomplex accumulate?
Sub-epithelial
3 main causes for Nephritic syndrome
Endocapillary proliferative GN
Membranoproliferative GN
Crescentic GN
