L24: STD - shortened Flashcards
Lymphogranuloma Venereum (LGV), Genital Herpes, Syphilis, and Chancroids are:
A. Genital Ulcer Disease
B. Warts, Papillomas
C. Cervicitis, Urethritis, and PID
A. Genital Ulcer Disease
True or False: N. gonorrhea and Chlyamydia belong to Cervicitis, Urethritis, and PID
True
Which gram-negative spirochete—which is ONLY visible by dark field microscopy—pathogen is responsible for causing syphilis?
Treponema pallidum
Primary syphilis is the initial latent period while tertiary syphilis is associated with which three symptoms?
- Gumma
- Cardiovascular Syphilis
- Neurosyphilis
Painless induration is associated with which stage of syphilis?
A. Primary stage
B. Secondary stage
C. Tertiary stage
A. Primary stage
True or False: Hard chancre/genital ulcer develops at point of entry in primary stage of syphilis
True
Which stage of syphilis resolves with or without treatment and highly infectious lesions?
Secondary Stage
Which stage is patient still infectious with syphilis? when are they no longer infectious?
Early Latent = still infectious
Late Latent = not infectious
When do most secondary syphilis relapses occur?
A. Early Latent
B. Late Latent
A. Early Latent
Which stage of syphilis is associated with slow, progressive inflammatory disease affecting any organ system + is REFRACTORY to abx therapy ?
Tertiary (Late) Stage
Which form of syphilis can be transmitted in utero, via placenta, at any stage of pregnancy
Syphilis Congenital Form (CS)
True or False: A patient is 2 years of age with congenital form of syphilis. They have the perinatal form
True
Hard chancre and genital ulcer suggests….
Syphilis
Which drug can treat all three stages of syphilis?
A. Methotrexate
B. Penicillin
B. Penicillin
How does one prevent congenital syphilis?
Benzathine penicillin >1 month prior to birth
____: A reaction that occurs s/p initial syphilis treatment, associated with flu-like symptoms
Jarisch-Herxheimer Reaction
True or False: Jarisch-Herxheimer Reaction usually occurs s/p initial syphilis treatment and is an endotoxic shock like response
True
- Rarely fatal
- Related to release of components by dead or dying trponemes
Which pathogen causes soft, but painful, chancre?
H. ducreyi
Chancroid increases the risk of developing __
HIV
A patient has a painful, soft ulcer and local lymphoadenitis. Upon gram staining, you see a “school of fish arrangement,” which suggests…
Chancroid
Which pathogen causes Lymphogranuloma Venereum?
A. Treponema pallidum
B. Chlamydia trachomatis
B. Chlamydia trachomatis
Three stages of LGV?
Primary Lesion
Inguinal (secondary) syndrome
Tertiary Stage
Which pathogen causes herpes? Can it be latent?
HSV
- Yes!
Syncytia formation suggests which condition? Treatment (but not cure)?
Genital Herpes
- Acyclovir
