L3: TB

Question 1

Intro to TB

Answer 1

• Tuberculosis is one of serious respiratory infectious diseases, that lead to pulmonary tuberculosis and may extend to extra pulmonary sites.

Question 2

Causative Organism of TB

Answer 2

Question 3

Characters of TB Bacilli

Answer 3

Question 4

TB Bacilli is Suseptible to …….

Answer 4

Question 5

Sources of Infection by TB

Answer 5

Question 6

Sources of Infection by TB

• Human

Answer 6

Question 7

Sources of Infection by TB

• Animal

Answer 7

• Via milk & other excreta.

Question 8

Factors Affecting Development of TB

Answer 8

Question 9

Factors Affecting Development of TB

• Source

Answer 9

Question 10

Factors influence infectivity of a particular patient:

Answer 10

Question 11

Factors Affecting Development of TB

• Mycobacterial

Answer 11

• Number of bacilli.
• Virulence of the infecting organism.

Question 12

Factors Affecting Development of TB

• Host

Answer 12

Question 13

Host Factors Affecting Development of TB

• race

Answer 13

More in black people.

Question 14

Host Factors Affecting Development of TB

• age

Answer 14

• Adolescents
• Old age.

Question 15

Host Factors Affecting Development of TB

• Environment

Answer 15

• Silica workers
• Overcrowding
• Direct contacts with TB cases.

Question 16

Host Factors Affecting Development of TB

• Habits

Answer 16

• Alcohol
• Smoking.

Question 17

Host Factors Affecting Development of TB

• Immunity

Answer 17

• Steroids and cytotoxic drugs.
• Diabetes.
• After gastrectomy.
• Malnutrition.
• Organ transplantation,
• Lymphoma and other malignancy.

Question 18

Pathology of TB

Answer 18

Question 19

Pathology of TB

• hallmark lesion

Answer 19

Question 20

Types of Pulmonary TB

Answer 20

Question 21

Primary TB

• Components of Primary Complex

Answer 21

• Ghon’s focus: TB granuloma
• Lymphangitis.
• TB lymphadenitis

Question 22

Primary TB

• Fate of Primary Complex

Answer 22

Question 23

Fate of Primary Complex

• 90%

Answer 23

Healing

Question 24

Fate of Primary Complex

• 10%

Answer 24

Question 25

Spread of Primary Complex - Enlargement of the Ghon's focus

Answer 25

Question 26

Spread of Primary Complex - Lymph node spread

Answer 26

Question 27

**Post-Primary TB** - Infection May be ....

Answer 27

- Endogenous - Hematogenous spread - Reactivation - Exogenous (reinfection).

Question 28

**Post-Primary TB** - Site

Answer 28

**Usually upper lung zones** - due to high ventilation/perfusion ratios with higher alveolar PO2 relative to other sites.

Question 29

**Post-Primary TB** - Types of Lesions

Answer 29

- Fibrotic type - Chronic fibro-caseous type

Question 30

Types of Lesions in **Post-Primary TB** - Fibrotic Type

Answer 30

small lesion that pass rapidly to fibrosis.

Question 31

Types of Lesions in **Post-Primary TB** - Chronic fibro-caseous type

Answer 31

Question 32

Spread of **Post-Primary TB**

Answer 32

Question 33

Spread of **Post-Primary TB** - Multiple TB Cavities

Answer 33

...

Question 34

Spread of **Post-Primary TB** - Miliary TB

Answer 34

Question 35

Spread of **Post-Primary TB** - Simon's Foci

Answer 35

Question 36

Spread of **Post-Primary TB** - Corticopleural TB

Answer 36

...

Question 37

Spread of **Post-Primary TB** - Tuberculoma

Answer 37

single pulmonary nodule.

Question 38

Spread of **Post-Primary TB** - Pleura

Answer 38

Pleurisy with effusion.

Question 39

Spread of **Post-Primary TB** - Pericardium

Answer 39

Pericardial effusion.

Question 40

Spread of **Post-Primary TB** - Lymph Glands

Answer 40

Hilar adenopathy.

Question 41

Spread of **Post-Primary TB** - Others

Answer 41