L4: CIN Flashcards
(33 cards)
1
Q
Def of CIN
A
- Locally malignant tumor of cervical epithelium not invading the basement membrane.
2
Q
Incidence of CIN
A
- The disease is more common in young ages “25-35 years” that are sexually active.
3
Q
Etiology & RF for CIN
A
4
Q
Etiology & RF for CIN
- STDs
A
5
Q
Etiology & RF for CIN
- Smoking, alcoholics and drug abuse
A
…
6
Q
Etiology & RF for CIN
- Prolonged hormonal contraception with HPV infection.
A
….
7
Q
Etiology & RF for CIN
- Immune-suppression and AIDS
A
…..
8
Q
Pathology of CIN
A
9
Q
Pathology of CIN
- NE
A
10
Q
Pathology of CIN
- ME
A
11
Q
Symptoms of CIN
A
12
Q
Symptoms of CIN
- Asymptomatic
A
- In most patients and accidentally discovered on routine screening.
13
Q
Symptoms of CIN
- Bleeding “Vaginal”
A
Post-coital bleeding or vaginal spotting or even discharge.
14
Q
Signs of CIN
A
15
Q
Signs of CIN
- Local
A
16
Q
INVx for CIN
A
17
Q
INVx for CIN
- Histopathology
A
18
Q
Histopathology in CIN
- Cervical cytology by Ayer’s spatula OR cyto-brush
A
19
Q
Histopathology in CIN
- Visual inspection with Acetic Acid “VIA test”
A
20
Q
Histopathology in CIN
- Colposcopy and Colposcopic guided biopsy
A
21
Q
Histopathology in CIN
- Endocervical curettage
A
22
Q
TTT of CIN
A
23
Q
TTT of CIN
- Prophylactic
A
24
Q
TTT of CIN
- Active
A
25
Active TTT of **CIN**
- Ablative
**Ablative procedures (failure rate 5 - 10%):**
- Cryotherapy, laser ablation or diathermy coagulation.
26
Active TTT of **CIN**
- Escisional
**Excisional procedures (failure rate < 5):**
- O LEEP (Loop Electrosurgical Excision Procedure).
- Laser conization.
- Cold knife conization.
- Surgical conization of the cervix.
27
Follow up of **CIN**
28
Follow up of **CIN**
- Schedule
- Every 3 - 6 months for 1st 2 yrs.
- Every year for 5 yrs if persistently negative.
29
Follow up of **CIN**
- Time of Recurrence
Most recurrences occur during the first 2 years after therapy.
30
Follow up of **CIN**
- TTT of Recurrent CIN
31
Natural Hx of **CIN** Acc to degree
32
Suspicous Features of CIN
33
Criteria to Exclude Invasive Carcinoma
