L2: Endometriosis & Adenomyosis Flashcards
(62 cards)
1
Q
Def of Endometriosis
A
- Presence of endometrial tissue (glands & stroma outside normal uterine cavity.
2
Q
Incidence of Endometriosis
A
- Accurate assessment of incidence is difficult because laparoscopy & laparotomy are needed for diagnosis (it is found in 5-30% of all laparoscopies)
3
Q
Etiology of Endometriosis
A
4
Q
Etiology of Endometriosis
- Implantation (transplantation) theory
A
5
Q
Etiology of Endometriosis
- Celomic metaplasia theory
A
- Endometriosis develops from metaplasia of cells lining pelvic peritoneum.
- No clinical or experimental support to this theory.
6
Q
Etiology of Endometriosis
- Vascular lymphatic theory
A
- Endometrium is transported via vascular & lymphatic systems.
- Evidence: Occurrence of endometriosis at distant sites (as umbilicus or Lungs
7
Q
Etiology of Endometriosis
- Genetic factor
A
- Risk is 7 times greater if ist degree relative has endometriosis.
8
Q
Etiology of Endometriosis
- Immunologic Factors
A
- Immune system may be altered in women è endometriosis because of decreased cell mediated cytotoxicity allowing endometrial cells to survive outside endometrial cavity.
9
Q
PPT Factors for Endometriosis
A
10
Q
Sites of Endometriosis
A
11
Q
Sites of Endometriosis
- Most Common
A
12
Q
NE of Endometriosis
A
13
Q
ME of Endometriosis
A
14
Q
CP of Endometriosis
A
15
Q
CP of Endometriosis
- Symptoms
A
16
Q
Symptoms of Endometriosis
- Asymptomatic
A
….
17
Q
Symptoms of Endometriosis
- Pelvic Pain
A
18
Q
Symptoms of Endometriosis
- Infertility
A
19
Q
Symptoms of Endometriosis
- Dys-Group
A
20
Q
Symptoms of Endometriosis
- Menstrual Disturbances
A
As menorrhagia or polymenorrhagia.
21
Q
Signs of Endometriosis
A
refer to the gross appearance above.
22
Q
INvx for Endometriosis
A
23
Q
INvx for Endometriosis
- Laparoscope
A
24
Q
INvx for Endometriosis
- Lab
A
Serum CA 125 “increased in endometriosis.
25
INvx for **Endometriosis**
- Rad
26
INvx for **Endometriosis**
- Histopathology (Bx)
ME
27
Prophylaxis for **Endometriosis**
28
Active TTT of **Endometriosis**
29
Active TTT of **Endometriosis**
- Expectant Medical TTT
30
Expectant Medical TTT **Endometriosis**
- NSAIDs
as pain killers and being anti-PGs.
31
Expectant Medical TTT **Endometriosis**
- Ovarian Suppression
32
Ovarian Suppresion as TTT of **Endometriosis**
- Pseudo-Pregnancy
33
Ovarian Suppresion as TTT of **Endometriosis**
- Pseudo-Menopause
34
Danazol in TTT of **Endometriosis**
- Structure
- Eff
- MOA
- SE
35
GnRH Agonists in TTT of **Endometriosis**
- Examples
- MOA
- SE
36
GnRH Antagonists in TTT of **Endometriosis**
- Examples
- Route of Adminstration
- Advantages
37
Surgical TTT of **Endometriosis**
38
Surgical TTT of **Endometriosis**
- Conservative
39
Conservative Surgical TTT of **Endometriosis**
- Indications
- young age needing further pregnancy.
40
Conservative Surgical TTT of **Endometriosis**
- Methods
41
Radical Surgical TTT of **Endometriosis**
42
Radical Surgical TTT of **Endometriosis**
- Indications
43
Radical Surgical TTT of **Endometriosis**
- Methods
44
Def of **Adenomyosis**
- It is the presence of endometrial glands and stroma in the myometrium, with adjacent smooth muscle hyperplasia.
45
Incidence of **Adenomyosis**
- Total
- Age
- Parity
- Race
46
Etiology of **Adenomyosis**
47
NE of **Adenomyosis**
48
ME of **Adenomyosis**
49
CP of **Adenomyosis**
50
CP of **Adenomyosis**
- Symptoms
51
CP of **Adenomyosis**
- Signs
52
INVx for **Adenomyosis**
53
INVx for **Adenomyosis**
- US
54
INVx for **Adenomyosis**
- MRI
55
INVx for **Adenomyosis**
- Hysteroscopy
Sub endometrial cysts.
56
INVx for **Adenomyosis**
- Laparoscsopy
.....
57
INVx for **Adenomyosis**
- Histopathology
Mostly from hysterectomy specimen
58
TTT of **Adenomyosis**
- Prophylactic
avoidance of predisposing factors
59
TTT of **Adenomyosis**
- Active
60
Active TTT of **Adenomyosis**
61
Active TTT of **Adenomyosis**
- Medical
62
Active TTT of **Adenomyosis**
- Surgical
