Lecture 1 Flashcards

1
Q

a cell is a fundamental unit of –

A

living matter

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2
Q

all living things are made up of –

A

cells

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3
Q

what is the fundamental feature of a cell?

A

ability to reproduce successfully

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4
Q

All cells contain the same three macromolecules – to carry out their fundamental properties of life

A

DNA, RNA, and protein

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5
Q

macromolecules are

A

made up of monomers connected by covalent bonds (polymers)

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6
Q

genetic info flows from

A

DNA –> RNA –> protein

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7
Q

every time a cell divides, – occurs so that all cells should have the same DNA

A

DNA replication

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8
Q

gene expression =

A

transcription + translation

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9
Q

all cells store – in the same linear chemical code - the DNA

A

hereditary info

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10
Q

Why is DNA more suitable than RNA to carry genetic info?

A

RNA has a hydroxyl group in the 2’ position of its ribose sugar which is very reactive

DNA does not have a hydroxyl group in the 2’ position of its deoxyribose and is therefore more stable

DNA also forms a stronger double helix (while RNA is single-stranded) and the hereditary info can be replicated by templated polymerization

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11
Q

all cells replicated DNA by

A

templated polymerization

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12
Q

– provides a way to make two molecules of genetic info exactly the same

A

double-stranded

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13
Q

2 strands of a DNA double helix are pulled apart and each serves as a template fro the synthesis of a new -

A

complementary strand

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14
Q

DNA is not synthesized as a free strand in isolation but on a – formed by a preexisting DNA strand

A

template

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15
Q

during growth, eukaryotic cells continually progress through – stages of the cell cycle, generating new daughter cells

A

four

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16
Q

resting cells

A

G0

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17
Q

RNA and protein synthesis

A

G1/G2

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18
Q

DNA replication

A

S

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19
Q

Cell division

A

M

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20
Q

T/F: cell division produces two daughter cells with identical hereditary material (DNA)

A

true

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21
Q

All cells transcribe – of their hereditary information into the same intermediate form - RNA

22
Q

template to make protein

23
Q

DNA is protected in the –

24
Q

translation occurs in the –

25
RNA is the suitable template for proteins because
RNA transcripts are mass produced and disposable
26
many different sets of RNA molecules can be made by -- different parts of a cell's DNA sequence
transcribing
27
different types of cells can use the same info --
differently
28
A nucleotide pairing between different region s of the -- RNA polymer chain causes the molecule to adopt a distinctive shape
same
29
all cells use -- as catalysts
proteins
30
like nucleic acid, proteins are long unbranched --
polymers
31
A feedback loop that connects proteins and polynucleotides form the basis or -- of living organisms
autocatalytic, self-reproducing behavior
32
info in the sequence of mRNA is read out in 3 nucleotides at a time =
codon
33
codon specifies a single --
amino acid
34
T/F: There are 64 possible codon all of which occur in nature
true
35
there are only -- naturally occurring AA
20
36
T/F: several codons correspond to the same AA
true
37
tRNA is attached to a -- at one end and an anticodon at the other end that corresponds to a particular codon in mRNA
amnio acid
38
ribosomes are a large multi molecular machine composed of
protein and rRNA
39
segment of the DNA sequence corresponding to a single protein or a single catalytic, regulatory, or structural RNA molecule
gene
40
in all cells, the -- are regulated
expression of individual genes
41
stretches of -- are intersperse among coding DNA
regulatory DNA
42
totality of genetic info in the complete DNA sequence
genome
43
Why is glucose not the main source of energy?
1 glucose = a lot of ATP | burn glucose --> waste a lot of energy
44
-- is the chemical currency of cells
ATP
45
all cells are enclosed in a
plasma membrane
46
membrane is formed by -- phospholipid molecules
amphiphilic
47
in an aqueous environment, phospholipids spontaneously form a lipid bilayer because it's
thermodynamically favorable
48
advantages of plasma membrane
protect cell, control what goes in and out (selectively permeable)
49
phospholipids spontaneously aggregate in water to create a bilayer that forms --
closed vesicles
50
hox genes were -- during evolution
conserved
51
Drosophila eyeless and Human Pax6 are examples of
conserved genes