Lecture 2 Flashcards
(16 cards)
Insulin:
- What is it
- Where is it from
- When is it secreted
- What does it do?
- Increase or Decrease EI
- Long term or short term?
- Agonist or Antagonist
- Peptide hormone
- From Pancreas (Beta cells)
- Secreted when blood glucose increases
- Increases blood glucose uptake so blood glucose can be stored as fat or glucagon
- EI increases if Hypoglycemic / EI decreases otherwise
- Long Term
Leptin:
- What is it
- Where is it from
- When is it secreted
- What does it do
- Increase or decrease EI
- Long term or short term
- Agonist or antagonist
- Obese Gene
- Adipose tissue
- During fasting or weight loss
- Is Anorexigenic, tracks fasting/feeding based on fat cell size
- Decreases EI ONLY if Leptin Deficient in humans
- Long term hormone
- Agonist
Ghrelin:
- What is it
- Where is it from
- When is it secreted
- What does it do?
- Increase or Decrease EI
- Long term or short term?
- Agonist or Antagonist
- Peptide Hormone
- From Fundus of Stomach
- Secreted during fasting
- Stimulates Growth Hormone (GH) and increases EI
- Increase EI
- Short Term
- Antagonist
Peptide YY (PYY):
- What is it
- Where is it from
- When is it secreted
- What does it do?
- Increase or Decrease EI
- Long term or short term?
- Agonist or Antagonist
- Peptide Hormone
- Secreted from Large/Small intestine
- Released after feeding
- Reduces food intake NOT SATIETY
- Decrease EI (anorexigenic)
- Short term
- Agonist
Cholecystokinin (CCK):
- What is it
- Where is it from
- When is it secreted
- What does it do?
- Increase or Decrease EI
- Long term or short term?
- Agonist or Antagonist
- Gut Hormone
- From Large and small intestine
- Released during and after feeding
- Inhibits feeding and synergize with leptin
- Decrease EI
- Short
- Agonist
Glucagon Like Peptide 1 (GLP1):
- What is it
- Where is it from
- When is it secreted
- What does it do?
- Increase or Decrease EI
- Long term or short term?
- Agonist or Antagonist
- Gut Hormone
- Small and Large Intestine
- Released after feeding
- Inhibits feeding, increase insulin, suppress glucagon
- Decrease EI (anorexogenic)
- Short Term
- Agonist
What are the 6 variables associated with body fat that may be regulated?
Body Weight, Body Temp, Energy Expenditure, Body Fatness, Energy intake, and energy balance
3 reasons for eating food?
Homeostasis
Pleasantness
Emergency (hypoglycemia, stress etc)
What is hunger
Sensations that promote food consumption (multidimensional)
What is satiation
While eating, the sensations that govern meal size and duration and also contribute to cessation of eating
What is satiety
sensations that determine the intermeal period of fasting (fullness between meals)
What is orexigenic
stimulating effect on appetite
what is anorexigenic
causing loss of appetite
What is an agonist
Drug/chemical that binds to a receptor to produce a reaction that naturally occurs –>helps a process occur
What is an antagonist?
A drug or chemical that binds to a receptor that blocks the natural occurance –> Inhibits a reaction from happening
What is the most common method of measuring an appetite?
A questionnaire, specifically the visual analogue scale