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Tissue Engineering and Regenerative Medicine > Lecture 2 > Flashcards

Lecture 2 Flashcards

1
Q

What are the different types of regeneration?

A

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2
Q

Define Regeneration?

A

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3
Q

Define Homeostatic regeneration?

A

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4
Q

Define injury induced or facultative regeneration?

A

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5
Q

What cells can do the regeneration? Which types specifically?

A

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6
Q

Define Homeostasis?

A

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7
Q

Define Facultative?

A

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8
Q

What is facultative regeneration? What animals can do this?

A

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9
Q

Define regeneration? Define repair?

A

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10
Q

What are the types of facultative regeneration?

A

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11
Q

What is epimorphosis?

A

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12
Q

What is morphallaxis?

A

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13
Q

What is compensatory regeneration?

A

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14
Q

How does salamander limb regeneration occur? What type of regeneration is it?

A

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15
Q

What is the process of salamander limb regeneration? What is needed?

A

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16
Q

What are the nerves doing during this limb regeneration process? What is released?

A

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17
Q

What happens if you denervate a limb stump? What happens if you add in nAG after denervating a limb after chopping it off?

A

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18
Q

How does a blastema form? What does it form as a result of?

A

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19
Q

What happens after blastema formation?

A

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20
Q

How does specification happen from the undifferentiated blastema? What genes are involved?

A

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21
Q

What type of cells can change into other cells after amputation during regeneration? Why?

A

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22
Q

How is positional memory maintained? What does this result in after amputation?

A

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23
Q

What is the retinoic acid gradient? What is a consequence of this?

A

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24
Q

What does retinoic acid expression control?

A

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25
Q

What levels of retinoic acid do the different blastema express? What does this result in?

A

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26
Q

What happens if a proximal blastema is removed and a distal blastema is grafted to proximal stump?

A

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27
Q

What is proximal-distal deletion?

A

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28
Q

What happens is a proximal blastema is placed on a distal stump? Why?

A

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29
Q

What is proximal-distal duplication? What does it lead to in salamanders?

A

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30
Q

Where is there intercalation? Where is there not intercalation?

A

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31
Q

How can the retinoic acid disrupt the proximal-distal axis?

A

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32
Q

Why do you not give vitamin A to a pregnant lady?

A

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33
Q

How does intercalation happen in insects? How is it different to the salamander?

A

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34
Q

If you add retinoic acid to a distal blastema what would happen?

A

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35
Q

What regeneration occurs in the Liver? Why?

A

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36
Q

How does “regeneration” happen in the liver?

A

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37
Q

What is morphallaxis? What is an example?

A

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38
Q

What in humans potentially be an example of morphallaxis?

A

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Tissue Engineering and Regenerative Medicine (17 decks)

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