Lecture 2 - Bioinformatics Flashcards Preview

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Flashcards in Lecture 2 - Bioinformatics Deck (13):
1

What is biomedical informatics?

Science of information as applied to, or studied in the context of biomedicine

2

Difference between bioinformatics and health informatics

Bioinformatics deals with molecular data.
Health informatics deals with clinical, patient-generated data.

3

What are ontologies?

Ways of visualising bioinformatic information

4

Potential new disease taxonomy from bioinformatics

According to causative gene or protein

5

Number of bioinformatic databases

Roughly 1500

6

Focus of Japanese bioinformatic databases

Metabolic

7

Focus of Swiss bioinformatic databases

Protein

8

Focus of European/US bioinformatic databases

Broad

9

Approaches to finding bioinformatic information
1)
2)
3)

1) Access a catalogue
2) Use an integrated search engine
3) Directly access databases

10

Example of a bioinformatic catalogue

NAR publishes an annual issue on databases, which are catalogued based on a series of parameters.

11

Example of an integrated search engine

NCBI Entrez

12

Field where bioinformatics is particularly useful

Rare genetic diseases (~8000 known)

13

Challenge for clinicians in bioinformatics

Navigating the large number of resources.
Discerning quality and reliability of resources