lecture 20 Flashcards
what is the impact of these transposable elements on the genome
on integrity and functional capacity of genome
are transposable elements abundant in large genomes and explains
yessss, 3 main categories of TEs in human genome
lines - class 1 autonomous (retrovirus derived, lost env gene so trapped inside genome of host, just moves around) = 21% of genome
sines - class 1 nonautonomous = 13%
dna transposons - class 2 auto and nonauto = 3%
there is around 20 times as much dna in human genome derived from transposable elements as there is dna encoding all human proteins (all protein coding genes)
big genomes = many TEs
what do TEs in plants account for
differences in genome size
general trend = big genome so many TEs
all descend from ancestral grass = leads to diff types
more TEs between genes
genome so big since all accumulated elements
where are TEs usually found
introns or intergenic regions
concentrated between genes
or within introns
why do you think transposable element insertions are usually found in introns or between genes
a
can TEs affect genes
a
give ex of TEs affecting genes - line 1
a
give ex of TEs affecting genes - alu element
a
what feature of TEs is associated with cancers and explains
a
what are TEs a source of
a
what are TEs a source of = ex of moths
a
describe genome surveillance
a
how were drosophila p elements discovered
a
explain drosophila p elements experiment - f1 and f2 dysgenic cross
a
explain drosophila p elements experiment - f1 and f2 reciprocal cross
a
