lecture 22

Question 1

what are mutations

Answer 1

a

Question 2

where do most mutations occur

Answer 2

a

Question 3

what types of mutations can be passed on

Answer 3

a

Question 4

describe inherited mutations

Answer 4

a

Question 5

Why will only half of the F1 individuals carry the mutation?

Answer 5

a

Question 6

what is a mutation

Answer 6

a

Question 7

what can mutations be

Answer 7

a

Question 8

Explain how mutations can be a source of genetic variation

Answer 8

a

Question 9

name the 3 types of scales of mutations

Answer 9

a

Question 10

describe chromosomal mutation

Answer 10

a

Question 11

describe insertional mutation

Answer 11

a

Question 12

describe point mutation

Answer 12

a

Question 13

name categories of point mutations - 2

Answer 13

a

Question 14

describe base sub point mutations

Answer 14

a

Question 15

describe the consequences of point mutations in open reading frames - synonymous mutations

Answer 15

a

Question 16

describe the consequences of point mutations in open reading frames - nonsynonymous mutations

Answer 16

a

Question 17

describe the consequences of point mutations in open reading frames - nonsense mutations

Answer 17

a

Question 18

describe the consequences of point mutations in open reading frames - frameshift mutations

Answer 18

a

Question 19

describe what happens when single base sub

Answer 19

a

Question 20

describe what happens when single base insertion or deletion

Answer 20

a

Question 21

do all point mutations have same effect and explain

Answer 21

a

Question 22

describe wild type function

Answer 22

a

Question 23

describe loss of function

Answer 23

a

Question 24

describe gain of function

Answer 24

a

Question 25

give ex of loss of function

Answer 25

a

Question 26

give ex of gain of function

Answer 26

a

Question 27

can sequences in non coding regions be important for gene function?

Answer 27

a

Question 28

describe consequences of point mutations in non-coding regions

Answer 28

a

Question 29

Why do some patients with a mutation in the PBRM1 gene have a worse prognosis?

Answer 29

a

Question 30

describe ex of BAP1

Answer 30

a

Question 31

describe Effect of point mutations on a gene’s mRNA and protein products

Answer 31

a

Question 32

describe consequences of point mutations within genes

Answer 32

a

Question 33

can mutations be spontaneous or induced

Answer 33

a

Question 34

describe origins of spontaneous mutations

Answer 34

a

Question 35

describe origins of spontaneous mutations - errors in base pairing

Answer 35

a