Lecture 22 Unit 3 Flashcards

1
Q

where does the hypothalamus receive input from

A

cortex, thalamus, limbic system and internal organs

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2
Q

what does the hypothalamus do

A

provides a link between the external and internal environment and the endocrine system

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3
Q

what do the hypothalamus and pituitary work together to do

A

control almost all aspects of growth, development, metabolism, and homeostasis

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4
Q

how does the hypothalamus control the pituitary gland

A

with special hormones called releasing hormones and inhibiting hormones

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5
Q

how does the hypothalamus release other hormones directly into circulation

A

through the posterior pituitary

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6
Q

how does the hypothalamus make use of the nervous system

A

it may send motor impulses to various tissue effectors

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7
Q

how does the hypothalamus make use of the endocrine system

A

uses it as an effector by secreting releasing and/or inhibiting hormones

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8
Q

what do releasing and inhibiting hormones act on

A

target cells in the anterior pituitary

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9
Q

what do the 5 types of anterior pituitary cells release into circulation

A

7 tropic hormones

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10
Q

how many releasing/inhibiting hormones are there

A

about 7

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11
Q

what are the 5 main cell types of the anterior pituitary gland

A
  1. somatotrophs
  2. thyrotrophs
  3. lactotrophs
  4. gonadotrophs
  5. corticotrophs
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12
Q

what do somatotrophs do

A

secrete human growth hormone

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13
Q

what do thyrotrophs do

A

secrete thyroid stimulating hormone

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14
Q

what do lactotrophs do

A

secrete prolactin

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15
Q

what do gonadotrophs do

A

secrete follicle stimulating hormone and lutenizing hormone

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16
Q

what do corticotrophs do

A

secrete adrenocorticotropic hormone and melanocyte stimulating hormone

17
Q

what does growth hormone releasing hormone regulate

A

HGH

18
Q

what does growth hormone inhibiting hormone regulate

A

HGH or TSH

19
Q

what does gonadotropin releasing hormone regulate

A

lutenizing hormone and follicle stimulating hormone

20
Q

what does prolactin releasing hormone regulate

A

prolactin

21
Q

what does prolactin inhibiting hormone regulate

A

prolactin or melanocyte stimulating hormone

22
Q

what does corticotropin releasing hormone regulate

A

ACTH and MSH

23
Q

what does thyrotropin releasing hormone stimulate

A

TSH

24
Q

what does HGH do within target cells

A

increases synthesis of insulin like growth factors that act locally or enter blood stream

25
Q

what do insulin like growth factors do

A
  • increase cell growth and cell division by increasing the uptake of amino acids and synthesis of proteins
  • stimulate lipolysis in adipose tissue
  • decrease glucose use by most body cells so blood glucose levels remain high enough to supply the brain
26
Q

what are some stimuli for GHRH

A

hypoglycemia, deep sleep, decreased fatty acids and increase amino acids in blood, increased sympathetic stimulation

27
Q

what are some stimuli for GHIH

A

hyperglycemia, REM sleep, increased fatty acids and decreased amino acids in blood, obesity, low levels of thyroid hormones, high levels of hGH

28
Q

what does FSH do in females

A

stimulates secretion of estrogen and initiates the formation of follicles within the ovary

29
Q

what does FSH do in males

A

stimulate sperm production in testes

30
Q

what does LH do in females

A
  • secretion of estrogen and progesterone
  • ovulation
  • formation of corpus luteum
31
Q

what does LH do in males

A

secretion of testosterone

32
Q

what does prolactin cause

A

milk production during suckling

33
Q

what inhibits MSH release

A

PIH (dopamine)

34
Q

what does ACTH stimulate

A

release of cortisol from adrenal cortex

35
Q

what is ACTH release stimulated by?

A

hypoglycemia, physical trauma, and IL-1

36
Q

what does cortisol do

A

inhibits the release of CRH and ACTH

37
Q

what does TSH do

A
  • stimulates the synthesis and secretion of T3 and T4

- stimulate metabolic rate