Lecture 27 - Neural activity during sleep (TBC)

Question 1

____ (EEG) is a method for measuring electrical activity in the brain by means of electrodes placed on the scalp

Answer 1

Electroencephalography

Question 2

____ ____ ____ (LFP) is electrical activity generated at synapses which summate in space and time. They also ____ propagate through extracellular space and through skull and scalp to electrodes

Answer 2

Local field potential; passively

Question 3

When an animal is awake and attentive, the __ __ __ in the ____ is dominated by ____ oscillations (in rats: range from __-__Hz).

Answer 3

LFP; hippocampus; theta; 6-10

Question 4

Theta oscillations are particularly prevalent during ____ and during ____ ____ ____ (REM) sleep

Answer 4

locomotion; rapid eye movement

Question 5

Oscillations are described by their frequency and amplitude:
Frequency = ____/____
Amplitude = height from ____ to trough

Answer 5

Frequency = cycles/sec
Amplitude: height from peak to trough

Question 6

____-____ are generated by a large barrage of ____ input from CA__ and occur aperiodically

Answer 6

sharp-waves; excitatory; 3

Question 7

Layers of CA1 include: ____ ____ (SO), ____ ____ (SP), ____ ____ (SR), and ____ ____-____ (SLM)

Answer 7

Stratum oriens; Stratum pyramidale; Stratum radiatum; Stratum lacunosum-moleculare

Question 8

____ ____ (SO) contains pyramidal neuron basal dentrites, and is the outermost layer of CA1

Answer 8

Stratum oriens

Question 9

____ ____ (SP) contains pyramidal neuron somas, and is also the second outermost layer of CA1

Answer 9

Stratum pyramidale

Question 10

____ ____ (SR) contains approximately the proximal 75% of apical dendrites, which represents the middle layer of CA1

Answer 10

Stratum radiatum

Question 11

____ ____-____ (SLM) contains the distal aspect of the apical dendrites, and is the deepest part of CA1

Answer 11

Statum lacunosum-moleculare

Question 12

In CA1, ____ ____ (SR) primarily receives input from CA__, while ____-____ ____ (SLM) received input from the ____ cortex

Answer 12

stratum radiatum; 3; stratum lacunosum-moleculare; entorhinal

Question 13

____ are fast frequency oscillations during sharp-waves

Answer 13

ripples

Question 14

Two-stage model of hippocampus