Lecture 6: Connective Tissue Flashcards Preview

First Semester: Microscopic Anatomy > Lecture 6: Connective Tissue > Flashcards

Flashcards in Lecture 6: Connective Tissue Deck (61)
Loading flashcards...
1

Three types of connective tissue

Embryonic
Adult
Special

2

Two types of embryonic ct

Mesenchyme
Mucous

3

4 types of adult connective tissue

Loose
Dense
reticular
adipose

4

Three types of special connective tissue

Cartilage
Bone
Blood

5

6 functions of connective tissue

-Connect
-Suspend/give form/subdivide
-Insulation and storage
-Defend
-Provide nutrition
-Repair and regeneration

6

5 Clinical relevancies of connective tissue

-Trauma/healing
-Inflammation
-Edema
-Vitamin C deficiency
-Tumor terminology/development

7

Two components of ct

Cells
Matrix

8

Two types of cells of Ct

resident
transient

9

Three components of the matrix of the ct

Fibers
Ground substance
Tissue fluid

10

Resident cells

-embryonic mesenchyme cells
-Always there

11

Examples of resident cells

Fibroblasts
reticular cells
adipocytes
mesenchymal
macrophages
mast cells

12

Transient cells

-Hematopoietic stem cells
-Come and go

13

Examples of transient cells

plasma cells
leukocytes
neutrophils
eosinophils
basophils
lymphocytes

14

Fibroblasts form

collagenous, elastic, and reticular fibers of the matrix

15

Macrophages

-Resident phagocytic cell of ct
-Can survive months in tissue
-May be named by located

16

Macrophages origin

From monocytes in blood. Once it enters ct, it is called a macrophage

17

Macrophages may be named by

location
ex. osteoclasts in bone
ex. kupffer cells in liver

18

Degranulation of mast cells causes

symptoms of allergy

19

Collagen fibers

white, very tensile and strong, do not stretch

20

Elastic fibers

Yellow, weak, and elastic, stretch and recoil

21

What are the most numerous fibers in the CT and bone?

Collagenous fibers

22

Collagen fiber structure

Extracellular scleroprotein fibers composed of fibrils usually arranges in bundles of indefinite length

23

Collagen fibers represent ____% dry weight in humans

30

24

4 Primary Types of Collagen Fibers

-Type 1: Resists tensile forces. Found in bone, dentin, tendons.
-Type 2: Resists compression. Forms fibrils found in cartilage
-Type 3: Reticular fibers found in stroma of expandable organs such as spleen, lymph node, liver, CV system, and lymphatics
-Type 4: basement membrane (basal membrane)

25

4 main types of collagen synthesis

Fibroblasts
Chondroblasts
Osteoblasts
Odontoblasts

26

Procollagen

Formed in the fibroblast, cleaved to tropocollagen outside the cell and then assembled into collagen fibrils

27

What is an important cofactor in collagen synthesis?

Vitamin C

28

3 Properties of collagen

-High tensile strength
-Poor shear strength
-Can only stretch 5% of initial length

29

Elastic fibers

Individual branching and anastomosing fibers; pink in H E but not easily detected, more evident with special stain
Yellow in natural color

30

Size of elastic fibers

0.2 - 5 um diameter in loose ct
Up to 12um in elastic ligaments
Can stretch up to 2.5 times original length