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Flashcards in Leukemia Deck (13):
1

4 types of leukemia?

ALL AML CML CLL

2

What leukemias happen in midlife?

The M in AML and CML stands for midlife (actually myeloid, but pretend)

Age 55-65

3

Leukemia in children?

ALL

4

Leukemia in elderly?

CLL (chronic!)

5

Kid with bone pain, anemia, frequent infection?

What do you see on smear?

ALL Abundant blasts

PAS and TdT positive

6

What is Philadelphia chromasone?

t9;22

15% of adults ALL cases

Drug for it? imatinib

7

Auer rods? Where do you see those? KNOW THIS!!

Rods in the cells. in AML

8

What is a smudge cell?

CLL ruptured cell from slide prep b/c lymphocytes are ruptured

9

Auer rods?

AML!

10

What is blast crisis?

Mature myeloid cells to conversion immature blasts

In CML (looks like acute leukemia)

11

What do you see in CML smear?

Increased myeloid procurers but no smudge!

12

CML has what chromosome?

PHILE (while CreaM cheese ) 9;22. BCR ABL

tyrosine kinase always on

also rarely in ALL

13

Myelodisplastic syndrome is what on slide? can become slides

looks like teddy roosevelt glasses. Neutrophils hypolobulated