Flashcards in Toxicology Deck (23):
PTSD nightmare med?
Tylenol has 4 stages
First is first 24 hours and mailaise and n/v
II is 2-3 days and is LFTs PT and bill is up with RUQ tenderness
III is jaundice, hep encephalopathy, bleeding and renal failure and DEATH
III is recovery, 4 days-2 weeks
Beta blocker toxic tx?
Fluids for hypotension, Atropine for heart rate
Glucagon activates adenylate cyclase and more calcium
Insulin and glucose to fix myocite metabolism
Calcium channel blocker tx?
Same as beta
fluids, atropine, glucagone, calcium, insulin and glucose
Almond breath in obtunded patient?
Tx with sodium thiosulfate and hydroxocobalamin
Makes stuff you can pee out
Nitrate can be done to make methemoglobinemia to bind it
Delayed symptom of cyanide tox?
When is methemoglobinemia a good thing?
When treating cyanide poisoning. You give nitrates to induce it to bind it up
EKG changes with Dig toxciity??
Prolonged PR interval
Atrial tach with AV block!!!
isoniazid tx? Signs of toxic?
Neuropathy and hepatotoxicity
Methanol and ethylene glycol tox tx?
Fomepizole, dialysis or booze
Salicylate tox symtpms?
Tinnitus, hyperthermia (uncoupled oxidative phosphorylation), Respiratory alkalosis
Mixed resp all with metabolic acidosis with anion gap
Salicylate poison tx?
Sodium bicarb for acidosis
Sulfonyureas have long half life, so what?
So need to hospitalize if hypoglycemic and coming to ER because juice won't fix it
TCA ovedose tx?
what do you do 15 years after ingestion of alkali
EGD to look for squamous cells stuff
First thing you do if organophosphate poisoning?
Second thing is pralidoxime
Iron to is GI phase first, then latent, then shock with met acidosis, then hepatotoxicity then bowel obstruction
Treatment of anemia with peripheral neuropathy?
Think lead poisoning
Kids: succimer or IF SEVERE dimercaprol orEDTA (dimercaprol is also for mercury, so think for some metals it is used!)
Adults give succimer
Mercury poisoning. Signs?
Lots of swordfish, mental status change, tremor
Dimercaprol, succimer, penicillamine
TPA overdose tx?
Body packing toxicity treatment?
Polethylene glycol to get it out fast