Flashcards in LIMITATIONS AND TOOLS OF THIS FIELD Deck (5)
what does off target mean?
That your modification etc. reaches a target you didn't want it to.
Why can RNAi sequence cause degradation of non target mRNAs?
Because it is homologous
How much percent of transcripts can be off target when used as a trigger for PTGS?
Why can off target effects cause biosafety and environmentally issues?
Because it can affect entirely different organisms