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Biochem block 3 > Lipid 2 > Flashcards

Lipid 2 Flashcards

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1
Q

2.1

A

ankrin

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2
Q

1

A

spectrin

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3
Q

band 3

A

pump ass with anion transport(integral protein)

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4
Q

glycophorin

A

antigenic determinant of rbc

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5
Q

glycophorin

A

b/n 3 and 4.1

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6
Q

peripheal ext. proteins

A

1,2.1,2.2, actin

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7
Q

band 7

A

G3P hydrogenase

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8
Q

which band is inovlved in glycolysis

A

band 7

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9
Q

abundant antigen

A

glycophorin

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10
Q

100 sugars – organized in – polysaccharide chains

A

100 sugars – organized in 16 polysaccharide chains in glycophorin

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11
Q

carb sugar chain

A

on ext domain of glycophorin (70aa)

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12
Q

rich in charge

A

internal domain of Glycophorin

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13
Q

apolar hydrophobic AA

A

trans bilayer of glycophorin

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14
Q

rise residue of alpha helix

A

1.5 ang

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15
Q

35 ang

A

trans bilayer of glycophorin

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16
Q

greater temp

A

greater % uniform fluor cells(proteins)

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17
Q

TG

A

broken down into FA for cell uptake

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18
Q

once in cell

A

FA converts to TG or used for NRG

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19
Q

cholesterol made in liver and

A

converted to CE

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20
Q

apoliporproteins

A

A,B,C,E

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21
Q

apoliporproteins and lipids

A

plasma lipoproteins

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22
Q

Low density lipoproteins (LDL) –

A

bad cholesterol

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23
Q

High density lipoproteins (HDL

A

good cholesterol

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24
Q

exogenous fat delivery

A

CM

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25
VLDL
– endogenous fat delivery
26
LDL –
cholesterol delivery system
27
HDL
– cholesterol removal from cells
28
high density correlates with artherosclerosis
Ldl
29
STAtin
lower LDL higher HDL
30
tf cells can directly take up TG
F only take FA
31
OH group on cholesterol
makes ester bond with ester
32
lipid dec. and protein inc
as you go from CM to VLDL to LDL to HDL
33
has apo BCE
CM and VLDL
34
only apo B
LDL
35
apo ACE
HDL
36
as you go from CM to VLDL to LDL to HDL
size decreases
37
prigin in liver
VLDL and HDL
38
intestine origin
CM
39
VLDL catabolism origin
LDL
40
catabolized in adipose tissue
CM and VLDL
41
catabolized in Liver
LDL and HDL
42
catabolized in liver and all periphereal cells
LDL
43
carry TG
CM and VLDL
44
CE carried by
LDL
45
CE and phospholipids
carried by hdl
46
how to get rid of cholesterol
---\>liver--\> bile salts---\> SI---\> secreted in feces
47
– plasma enzyme (in the bloodstream)
LPL
48
breaks down TG→FA
LPL
49
activated as cofactor APO-C (CM and VLDL)
LPL
50
Lecithin cholesterol acyl transferase (LCAT
acyl chains on lecithin and transfers to cholesterol to make a CE
51
– activated by cofactor APO-A (HDL)
Lecithin cholesterol acyl transferase (LCAT
52
activated by cofactor APO-A (HDL) in the bloodstream
LCAT
53
takes acyl Co-A and cholesterol inside of liver cells
ACAT
54
in liver cell
ACAT
55
HMG Co-A Reductase
makes cholesterol the rate limiting step of cholesterol biosynthesis
56
Intracellular enzymes
HMG Co-A Reductase ACAT
57
in blood stream
LDL
58
LPL cofactor
apo C
59
APO-B –
ligand for LDL receptor
60
APO-A –
LCAT cofactor
61
APO-A –
ligand for 2 receptors/transporters ABCA1&SRB1
62
lipoprotein
phospholipid with apoprotein croplet containing TG and CE
63
apo protein
stabilize droplet and have act enzyme and transporters
64
chylomicron
made from interstinal mucosal cell
65
ACAT
Chol-\> CE in int. mucosal cell
66
apo protein C and E
CM
67
LPL
TG to FA in CM and transfers to adipose cels
68
once in Adipose cell
FA made back to TG
69
after CM delivers TG to adipose cell
it delivers CE to Liver
70
CM binds to liver thru
APo E
71
Liver make
TG from F CE FROM CHOL bile from Chol
72
VLDL
come from Liver
73
VLDL
apo B and C TG and CE
74
go to adipose tissues
LDL and VLDL
75
LPL acts in
LDL and VLDL to make FA and deliver to adipose tissue
76
after coming from adipose tissue
LDL is formed from VLDL
77
only hase apo B
LDL after adipose tissue
78
endocytosis
of LDL particle on Peripheal cell(CE in)
79
adrenal gland recieves
LDL and takes in CE to form Chol(make steroid hormones)
80
tf all cells have ability to make cholesterol
T but only liver and adrenal cells do
81
Liver secretes APO a
to another peripheal cell
82
ABCA1
transporter for APO A
83
Chol and phospholipid combined
with APO A1 to make HDL
84
SBR1
on liver and recieves HDL(with chol and phospholipid)

Biochem block 3 (12 decks)

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